CRCGN011_HEPG2_24H:M14 Gene Set
Genes
49 genes differentially expressed following the CRCGN011_HEPG2_24H:M14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MOK
|
MOK protein kinase
|
5.51545
|
|
GPATCH8
|
G patch domain containing 8
|
5.27348
|
|
CSK
|
c-src tyrosine kinase
|
4.91515
|
|
EVL
|
Enah/Vasp-like
|
4.79805
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.70355
|
|
TBXA2R
|
thromboxane A2 receptor
|
4.54711
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.089
|
|
NMU
|
neuromedin U
|
3.91685
|
|
CYCS
|
cytochrome c, somatic
|
3.8674
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.4125
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
3.3739
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.04605
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.9515
|
|
RRAGA
|
Ras-related GTP binding A
|
2.7363
|
|
OAS2
|
2'-5'-oligoadenylate synthetase 2, 69/71kDa
|
2.6758
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.53535
|
|
KCNA5
|
potassium channel, voltage gated shaker related subfamily A, member 5
|
2.40395
|
|
OAS3
|
2'-5'-oligoadenylate synthetase 3, 100kDa
|
2.2035
|
|
SCAF8
|
SR-related CTD-associated factor 8
|
2.15595
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.14725
|
|
COQ8A
|
coenzyme Q8A
|
2.141
|
|
PROSER1
|
proline and serine rich 1
|
2.12305
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.1108
|
|
ZNF589
|
zinc finger protein 589
|
2.09332
|
|
SPRY1
|
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
|
2.0332
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
2.00985
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.94605
|
|
LDHD
|
lactate dehydrogenase D
|
-4.88985
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.88625
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.95095
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.34522
|
|
CCNB2
|
cyclin B2
|
-3.31815
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.99145
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.943
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.78673
|
|
RNF167
|
ring finger protein 167
|
-2.66235
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.55259
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.54987
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.51835
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.45985
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.44095
|
|
CSF2
|
colony stimulating factor 2 (granulocyte-macrophage)
|
-2.42865
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.41365
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.3136
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.25708
|
|
MCMBP
|
minichromosome maintenance complex binding protein
|
-2.13455
|
|
CYRIA
|
CYFIP related Rac1 interactor A
|
-2.12727
|
|
CST4
|
cystatin S
|
-2.1214
|
|
KRT7
|
keratin 7, type II
|
-2.02305
|
