CRCGN011_HEPG2_24H:M16 Gene Set
Genes
40 genes differentially expressed following the CRCGN011_HEPG2_24H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
8.6288
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.1985
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.11475
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.0329
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.8548
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.8466
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.15295
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.90412
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.2267
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.59445
|
|
EVL
|
Enah/Vasp-like
|
2.5846
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
2.5694
|
|
GPATCH8
|
G patch domain containing 8
|
2.5386
|
|
FCHO1
|
FCH domain only 1
|
2.2742
|
|
JADE2
|
jade family PHD finger 2
|
2.20565
|
|
NMU
|
neuromedin U
|
2.135
|
|
FBXO11
|
F-box protein 11
|
2.12233
|
|
PEX6
|
peroxisomal biogenesis factor 6
|
2.09802
|
|
PGLS
|
6-phosphogluconolactonase
|
2.0535
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-7.44061
|
|
PTPN1
|
protein tyrosine phosphatase, non-receptor type 1
|
-5.32745
|
|
LDHD
|
lactate dehydrogenase D
|
-5.12975
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-5.0994
|
|
CCNB2
|
cyclin B2
|
-4.83715
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.695
|
|
MAP7
|
microtubule-associated protein 7
|
-4.5374
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-4.11724
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.91077
|
|
GRN
|
granulin
|
-2.8616
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.76645
|
|
IPO13
|
importin 13
|
-2.73565
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.68895
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.48865
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.35095
|
|
SOD3
|
superoxide dismutase 3, extracellular
|
-2.29385
|
|
SCYL2
|
SCY1-like 2 (S. cerevisiae)
|
-2.1613
|
|
RNF167
|
ring finger protein 167
|
-2.15985
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.0745
|
|
TNS4
|
tensin 4
|
-2.01685
|
|
POU2AF1
|
POU class 2 associating factor 1
|
-2.0024
|
