| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-(4-ethoxyphenyl)urea 1.33 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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86 genes differentially expressed following the CRCGN011_HEPG2_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.12505 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.1671 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.0614 |
| TLR4 | toll-like receptor 4 | 4.88515 |
| EPHB2 | EPH receptor B2 | 4.70096 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.58808 |
| RPL39L | ribosomal protein L39-like | 4.57255 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.44065 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.3518 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.16545 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 3.1603 |
| KIF5C | kinesin family member 5C | 3.0114 |
| SETD3 | SET domain containing 3 | 2.96575 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 2.818 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.62515 |
| ISL1 | ISL LIM homeobox 1 | 2.5796 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.53365 |
| DIPK1A | divergent protein kinase domain 1A | 2.52055 |
| PAAF1 | proteasomal ATPase-associated factor 1 | 2.49475 |
| OLFM4 | olfactomedin 4 | 2.40945 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.3742 |
| EPHA3 | EPH receptor A3 | 2.33295 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 2.3097 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.2705 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 2.2673 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 2.2228 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 2.2213 |
| MRPL33 | mitochondrial ribosomal protein L33 | 2.2094 |
| ACP3 | acid phosphatase 3 | 2.20305 |
| TBXAS1 | thromboxane A synthase 1 (platelet) | 2.19285 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 | 2.17875 |
| SNX7 | sorting nexin 7 | 2.1741 |
| FOXJ3 | forkhead box J3 | 2.15392 |
| PGAM2 | phosphoglycerate mutase 2 (muscle) | 2.14925 |
| NMU | neuromedin U | 2.14185 |
| NCF2 | neutrophil cytosolic factor 2 | 2.12 |
| CYCS | cytochrome c, somatic | 2.09785 |
| CEP57 | centrosomal protein 57kDa | 2.08139 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 2.07325 |
| LIFR | leukemia inhibitory factor receptor alpha | 2.05565 |
| TWIST1 | twist family bHLH transcription factor 1 | 2.0228 |
| MSMB | microseminoprotein, beta- | 2.02047 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -7.0542 |
| TRIB3 | tribbles pseudokinase 3 | -5.431 |
| LAP3 | leucine aminopeptidase 3 | -5.29815 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.18105 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.09845 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.01945 |
| CDC20 | cell division cycle 20 | -5.0 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7725 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -4.7107 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.7073 |
| MAP7 | microtubule-associated protein 7 | -4.56373 |
| DNM1L | dynamin 1-like | -4.46535 |
| SCAND1 | SCAN domain containing 1 | -4.3287 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.31325 |
| FAIM | Fas apoptotic inhibitory molecule | -3.5525 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.4598 |
| RNF167 | ring finger protein 167 | -3.26265 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.2601 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.03545 |
| HEATR1 | HEAT repeat containing 1 | -2.84923 |
| GDF15 | growth differentiation factor 15 | -2.74635 |
| DCK | deoxycytidine kinase | -2.5191 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.454 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 | -2.32915 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.32765 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -2.3124 |
| TNIP2 | TNFAIP3 interacting protein 2 | -2.3079 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.29175 |
| UGT1A8 | UDP glucuronosyltransferase 1 family, polypeptide A8 | -2.25265 |
| SPAG4 | sperm associated antigen 4 | -2.2324 |
| IP6K1 | inositol hexakisphosphate kinase 1 | -2.1944 |
| ZBED1 | zinc finger, BED-type containing 1 | -2.1777 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.1706 |
| CAPRIN2 | caprin family member 2 | -2.14975 |
| KLF6 | Kruppel-like factor 6 | -2.14278 |
| ALS2CL | ALS2 C-terminal like | -2.1109 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) | -2.07255 |
| LAD1 | ladinin 1 | -2.03225 |
| DUSP5 | dual specificity phosphatase 5 | -2.02115 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.0123 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -2.00493 |
| CA8 | carbonic anhydrase VIII | -2.0002 |
| WDR19 | WD repeat domain 19 | -2.00015 |
