CRCGN011_HEPG2_24H:M18 Gene Set
Genes
54 genes differentially expressed following the CRCGN011_HEPG2_24H:M18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.3886
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.35935
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
5.3493
|
|
CSK
|
c-src tyrosine kinase
|
4.91515
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.4672
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
4.44977
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.3713
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.86005
|
|
COL11A1
|
collagen, type XI, alpha 1
|
3.4108
|
|
KLHL9
|
kelch-like family member 9
|
2.7926
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.78595
|
|
PRR15L
|
proline rich 15-like
|
2.75605
|
|
JADE2
|
jade family PHD finger 2
|
2.58967
|
|
CCNF
|
cyclin F
|
2.48885
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.4833
|
|
RARRES1
|
retinoic acid receptor responder (tazarotene induced) 1
|
2.37695
|
|
TIMM8A
|
translocase of inner mitochondrial membrane 8 homolog A (yeast)
|
2.2879
|
|
LCN2
|
lipocalin 2
|
2.20995
|
|
SLC9A3R1
|
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
|
2.1336
|
|
GPATCH8
|
G patch domain containing 8
|
2.08595
|
|
MRPL44
|
mitochondrial ribosomal protein L44
|
2.0553
|
|
AHNAK2
|
AHNAK nucleoprotein 2
|
2.03155
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-9.5446
|
|
GNAS
|
GNAS complex locus
|
-7.41718
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-5.4168
|
|
GDF15
|
growth differentiation factor 15
|
-5.0
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.8359
|
|
CCNB2
|
cyclin B2
|
-4.6482
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.60665
|
|
SPAG4
|
sperm associated antigen 4
|
-4.1043
|
|
HMG20B
|
high mobility group 20B
|
-3.6866
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.4789
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-3.11151
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-3.06295
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-2.6985
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.63035
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.60545
|
|
VASH2
|
vasohibin 2
|
-2.39505
|
|
BSG
|
basigin (Ok blood group)
|
-2.33295
|
|
NETO2
|
neuropilin (NRP) and tolloid (TLL)-like 2
|
-2.2767
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.2555
|
|
ZNF586
|
zinc finger protein 586
|
-2.24165
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.23102
|
|
DHX38
|
DEAH (Asp-Glu-Ala-His) box polypeptide 38
|
-2.19085
|
|
OSBP2
|
oxysterol binding protein 2
|
-2.1778
|
|
GOLGA8A
|
golgin A8 family, member A
|
-2.1645
|
|
RMDN3
|
regulator of microtubule dynamics 3
|
-2.1027
|
|
MSX1
|
msh homeobox 1
|
-2.1013
|
|
BTBD2
|
BTB (POZ) domain containing 2
|
-2.0951
|
|
PEG10
|
paternally expressed 10
|
-2.0943
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.0636
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
-2.05065
|
|
RNF167
|
ring finger protein 167
|
-2.04065
|
|
RASL10A
|
RAS-like, family 10, member A
|
-2.0371
|
