| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sodium (e)-2-[4-(dimethylamino)phenyl]diazenesulfonate 21.71 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN011_HEPG2_24H:M19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 6.8136 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.15695 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.01455 |
| LCN2 | lipocalin 2 | 5.0 |
| EPHB2 | EPH receptor B2 | 4.78146 |
| HMOX1 | heme oxygenase 1 | 4.77885 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.32215 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.9603 |
| NMU | neuromedin U | 3.9462 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.36352 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.2755 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 3.15925 |
| TEX10 | testis expressed 10 | 2.90715 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.85815 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.82345 |
| MELK | maternal embryonic leucine zipper kinase | 2.81345 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.81273 |
| JADE2 | jade family PHD finger 2 | 2.73987 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.5587 |
| KLHL9 | kelch-like family member 9 | 2.47143 |
| VAT1 | vesicle amine transport 1 | 2.46905 |
| VGLL4 | vestigial-like family member 4 | 2.44602 |
| TXNRD1 | thioredoxin reductase 1 | 2.43435 |
| RNF167 | ring finger protein 167 | 2.34635 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.3424 |
| PLSCR3 | phospholipid scramblase 3 | 2.29215 |
| NOSIP | nitric oxide synthase interacting protein | 2.19425 |
| ZNF589 | zinc finger protein 589 | 2.1495 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.10547 |
| ERP29 | endoplasmic reticulum protein 29 | 2.1006 |
| THOP1 | thimet oligopeptidase 1 | 2.0964 |
| CBR1 | carbonyl reductase 1 | 2.09115 |
| CYCS | cytochrome c, somatic | 2.0844 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 2.0742 |
| CYB561D2 | cytochrome b561 family, member D2 | 2.05395 |
| LEFTY1 | left-right determination factor 1 | 2.00675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -7.2494 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.67975 |
| DNM1L | dynamin 1-like | -4.87305 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.6019 |
| CCNB1 | cyclin B1 | -4.5883 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.218 |
| CCNB2 | cyclin B2 | -4.2101 |
| ACOT9 | acyl-CoA thioesterase 9 | -4.2098 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.49565 |
| PCNA | proliferating cell nuclear antigen | -3.17815 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -2.5638 |
| ECT2 | epithelial cell transforming 2 | -2.5454 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.52775 |
| TTC33 | tetratricopeptide repeat domain 33 | -2.5258 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | -2.30973 |
| RPGR | retinitis pigmentosa GTPase regulator | -2.29825 |
| TENM1 | teneurin transmembrane protein 1 | -2.28225 |
| ACTL6A | actin-like 6A | -2.2614 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | -2.2549 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked | -2.18715 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) | -2.17875 |
| FBXO5 | F-box protein 5 | -2.16165 |
| COXFA4L2 | cytochrome c oxidase hypoxia associated subunit FA4L2 | -2.137 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -2.12275 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 | -2.0912 |
| SDC2 | syndecan 2 | -2.08492 |
| NAIP | NLR family, apoptosis inhibitory protein | -2.0726 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -2.0703 |
| MACIR | macrophage immunometabolism regulator | -2.0509 |
| RECQL | RecQ helicase-like | -2.05045 |
| KCNK7 | potassium channel, two pore domain subfamily K, member 7 | -2.03125 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -2.03095 |
| DEPP1 | DEPP autophagy regulator 1 | -2.01925 |
| LOC124905743 | low affinity immunoglobulin gamma Fc region receptor III-B | -2.0086 |
