| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sodium (e)-2-[4-(dimethylamino)phenyl]diazenesulfonate 2.71 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
66 genes differentially expressed following the CRCGN011_HEPG2_24H:M22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 5.8735 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.3215 |
| SQOR | sulfide quinone oxidoreductase | 4.9941 |
| RPL39L | ribosomal protein L39-like | 4.8419 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.7442 |
| UBQLN2 | ubiquilin 2 | 4.66275 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 4.14307 |
| NUP133 | nucleoporin 133kDa | 3.9212 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.4582 |
| EPHB2 | EPH receptor B2 | 3.44972 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.31073 |
| COL11A1 | collagen, type XI, alpha 1 | 2.76172 |
| GPATCH8 | G patch domain containing 8 | 2.74415 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.7217 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.65905 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.5604 |
| KDM5D | lysine (K)-specific demethylase 5D | 2.55745 |
| COQ8A | coenzyme Q8A | 2.5001 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.4795 |
| WASF3 | WAS protein family, member 3 | 2.3428 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 2.33265 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.3115 |
| SORBS3 | sorbin and SH3 domain containing 3 | 2.2928 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 2.2893 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 2.24973 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 2.24335 |
| LY6G6F-LY6G6D | LY6G6F-LY6G6D readthrough | 2.23705 |
| COA3 | cytochrome c oxidase assembly factor 3 | 2.22595 |
| TAOK1 | TAO kinase 1 | 2.2254 |
| TMSB4X | thymosin beta 4, X-linked | 2.1963 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 2.18975 |
| ZBED1 | zinc finger, BED-type containing 1 | 2.06795 |
| HSPA1A | heat shock 70kDa protein 1A | 2.0505 |
| CYCS | cytochrome c, somatic | 2.00885 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| CCDC86 | coiled-coil domain containing 86 | -5.08205 |
| CDC20 | cell division cycle 20 | -5.0 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.744 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.52925 |
| SLC35F2 | solute carrier family 35, member F2 | -4.4202 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.85605 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -3.44378 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.4019 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.3232 |
| BCAP29 | B-cell receptor-associated protein 29 | -2.99345 |
| MTA1 | metastasis associated 1 | -2.6945 |
| RNF167 | ring finger protein 167 | -2.63825 |
| PGM1 | phosphoglucomutase 1 | -2.59685 |
| DCK | deoxycytidine kinase | -2.5786 |
| CCNB2 | cyclin B2 | -2.5117 |
| SNX11 | sorting nexin 11 | -2.4182 |
| SCAND1 | SCAN domain containing 1 | -2.3458 |
| PLSCR4 | phospholipid scramblase 4 | -2.3405 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.27798 |
| RGS4 | regulator of G-protein signaling 4 | -2.24443 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.2166 |
| SYPL1 | synaptophysin-like 1 | -2.17482 |
| RET | ret proto-oncogene | -2.12133 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.1038 |
| TFF1 | trefoil factor 1 | -2.08145 |
| EDNRB | endothelin receptor type B | -2.06145 |
| RAPGEF4 | Rap guanine nucleotide exchange factor (GEF) 4 | -2.02975 |
| ATXN7L1 | ataxin 7-like 1 | -2.025 |
| FOXE1 | forkhead box E1 | -2.0197 |
| COG5 | component of oligomeric golgi complex 5 | -2.01622 |
| NTS | neurotensin | -2.00885 |
