CRCGN011_HEPG2_24H:M24 Gene Set
Genes
31 genes differentially expressed following the CRCGN011_HEPG2_24H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
5.4741
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
5.45975
|
|
NOTCH1
|
notch 1
|
5.32675
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.11545
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
4.69347
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.83545
|
|
PLSCR3
|
phospholipid scramblase 3
|
3.31037
|
|
EVL
|
Enah/Vasp-like
|
2.7293
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.7012
|
|
PMM2
|
phosphomannomutase 2
|
2.6721
|
|
NVL
|
nuclear VCP-like
|
2.45365
|
|
CHEK2
|
checkpoint kinase 2
|
2.41295
|
|
APP
|
amyloid beta (A4) precursor protein
|
2.27042
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.20065
|
|
STK10
|
serine/threonine kinase 10
|
2.15665
|
|
JADE2
|
jade family PHD finger 2
|
2.03172
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.0212
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-5.6801
|
|
LDHD
|
lactate dehydrogenase D
|
-5.064
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.49235
|
|
CCNB2
|
cyclin B2
|
-3.7221
|
|
GNAS
|
GNAS complex locus
|
-3.58591
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.4156
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.99725
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.89955
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.76045
|
|
RNF167
|
ring finger protein 167
|
-2.71855
|
|
GDF15
|
growth differentiation factor 15
|
-2.6391
|
|
CHEK1
|
checkpoint kinase 1
|
-2.61697
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.03245
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.0224
|
