| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | furan 38.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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89 genes differentially expressed following the CRCGN011_HEPG2_24H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.7055 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.3507 |
| E2F2 | E2F transcription factor 2 | 5.2534 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.88705 |
| TLR4 | toll-like receptor 4 | 4.8793 |
| CBR3 | carbonyl reductase 3 | 4.3123 |
| RPL39L | ribosomal protein L39-like | 3.98385 |
| LCN2 | lipocalin 2 | 3.1573 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 3.0106 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 2.98382 |
| PARP1 | poly (ADP-ribose) polymerase 1 | 2.98255 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.95975 |
| FASTKD5 | FAST kinase domains 5 | 2.8989 |
| CTSL | cathepsin L | 2.81535 |
| HMGA2 | high mobility group AT-hook 2 | 2.81495 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.67645 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 2.64545 |
| CCNF | cyclin F | 2.62842 |
| CDC45 | cell division cycle 45 | 2.55515 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.5396 |
| ZNF324 | zinc finger protein 324 | 2.38205 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 2.37435 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 2.354 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 2.35292 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 2.3054 |
| CRYZ | crystallin, zeta (quinone reductase) | 2.2737 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 2.2621 |
| ZNF589 | zinc finger protein 589 | 2.25253 |
| ANKRD10 | ankyrin repeat domain 10 | 2.25215 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma | 2.25017 |
| MTX1 | metaxin 1 | 2.21635 |
| ZNF516 | zinc finger protein 516 | 2.2101 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.202 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.19495 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.17915 |
| PLSCR3 | phospholipid scramblase 3 | 2.15342 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 | 2.14715 |
| GLCE | glucuronic acid epimerase | 2.12795 |
| OCRL | oculocerebrorenal syndrome of Lowe | 2.1137 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 | 2.08175 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.08015 |
| MACIR | macrophage immunometabolism regulator | 2.07945 |
| BAD | BCL2-associated agonist of cell death | 2.0698 |
| STX11 | syntaxin 11 | 2.06375 |
| GATA2 | GATA binding protein 2 | 2.05648 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 2.03977 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 2.0374 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 2.00367 |
| KIF1B | kinesin family member 1B | 2.0032 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| CDC20 | cell division cycle 20 | -5.31545 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.0672 |
| CCNB2 | cyclin B2 | -4.70835 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.42225 |
| LDHD | lactate dehydrogenase D | -4.33125 |
| USP6NL | USP6 N-terminal like | -4.3156 |
| SCAND1 | SCAN domain containing 1 | -4.285 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.24855 |
| CHMP4B | charged multivesicular body protein 4B | -3.91355 |
| ADI1 | acireductone dioxygenase 1 | -3.84795 |
| NGRN | neugrin, neurite outgrowth associated | -3.83165 |
| NVL | nuclear VCP-like | -3.8301 |
| GNAS | GNAS complex locus | -3.37991 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -3.25065 |
| IFRD2 | interferon-related developmental regulator 2 | -3.13333 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.99195 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.9533 |
| ZW10 | zw10 kinetochore protein | -2.90265 |
| RBM34 | RNA binding motif protein 34 | -2.70603 |
| STAMBP | STAM binding protein | -2.67455 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -2.5582 |
| LAMB3 | laminin, beta 3 | -2.5548 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -2.50645 |
| SNX11 | sorting nexin 11 | -2.50448 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -2.47005 |
| CTSZ | cathepsin Z | -2.41975 |
| CDCP1 | CUB domain containing protein 1 | -2.31495 |
| CCDC51 | coiled-coil domain containing 51 | -2.2951 |
| RGS2 | regulator of G-protein signaling 2 | -2.2701 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.2293 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.22425 |
| CLDN7 | claudin 7 | -2.14385 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -2.13655 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 | -2.12045 |
| SHARPIN | SHANK-associated RH domain interactor | -2.06345 |
| BAG6 | BCL2-associated athanogene 6 | -2.05848 |
| CTSD | cathepsin D | -2.01965 |
| KIF4A | kinesin family member 4A | -2.01305 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.0092 |
