CRCGN011_HEPG2_24H:N02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description furan 19.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

736 genes differentially expressed following the CRCGN011_HEPG2_24H:N02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 8.568
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 8.24525
KCNK1 potassium channel, two pore domain subfamily K, member 1 7.9311
C2CD2 C2 calcium-dependent domain containing 2 6.10165
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 5.52445
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 5.3336
PPARG peroxisome proliferator-activated receptor gamma 5.3099
CXCL2 chemokine (C-X-C motif) ligand 2 5.25575
SNAP25 synaptosomal-associated protein, 25kDa 5.17972
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.0097
CSK c-src tyrosine kinase 5.0
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.94605
ATP11B ATPase, class VI, type 11B 4.903
RPL39L ribosomal protein L39-like 4.80315
STK10 serine/threonine kinase 10 4.71373
TREM1 triggering receptor expressed on myeloid cells 1 4.66275
BTK Bruton agammaglobulinemia tyrosine kinase 4.56535
TLR4 toll-like receptor 4 4.46905
MYLK myosin light chain kinase 4.44115
CCL2 chemokine (C-C motif) ligand 2 4.2367
IL1B interleukin 1, beta 4.22398
NANOS3 nanos homolog 3 (Drosophila) 4.2231
MMP2 matrix metallopeptidase 2 4.02295
HOXA10 homeobox A10 3.99997
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.9558
COL11A1 collagen, type XI, alpha 1 3.9257
LOC122526780 uncharacterized LOC122526780 3.7987
CYCS cytochrome c, somatic 3.7711
CNKSR2 connector enhancer of kinase suppressor of Ras 2 3.7424
SLC35F5 solute carrier family 35, member F5 3.65755
EXOC6B exocyst complex component 6B 3.5948
TRAM2 translocation associated membrane protein 2 3.58817
PRKCH protein kinase C, eta 3.53227
POU4F2 POU class 4 homeobox 2 3.4918
MUC1 mucin 1, cell surface associated 3.48522
RFX3 regulatory factor X, 3 (influences HLA class II expression) 3.4839
MSH4 mutS homolog 4 3.4392
TAC1 tachykinin, precursor 1 3.39085
A4GNT alpha-1,4-N-acetylglucosaminyltransferase 3.3804
PDYN prodynorphin 3.28335
KIFBP kinesin family binding protein 3.2794
IL23A interleukin 23, alpha subunit p19 3.21535
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 3.1669
CDH9 cadherin 9, type 2 (T1-cadherin) 3.14115
SOX2 SRY (sex determining region Y)-box 2 3.1346
GFM1 G elongation factor, mitochondrial 1 3.12605
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 3.07032
DZIP1 DAZ interacting zinc finger protein 1 3.07005
IL10 interleukin 10 3.0684
FFAR2 free fatty acid receptor 2 3.06575
SPO11 SPO11 meiotic protein covalently bound to DSB 3.06365
NPHP1 nephronophthisis 1 (juvenile) 3.05195
IL24 interleukin 24 3.0519
SNAP91 synaptosomal-associated protein, 91kDa 3.05025
RAVER2 ribonucleoprotein, PTB-binding 2 3.04125
PHF14 PHD finger protein 14 3.02495
PECAM1 platelet/endothelial cell adhesion molecule 1 3.02122
TLL2 tolloid-like 2 3.0147
KIAA1549L KIAA1549-like 3.008
TGFB3 transforming growth factor, beta 3 2.98765
ANKRD7 ankyrin repeat domain 7 2.9874
SCN11A sodium channel, voltage gated, type XI alpha subunit 2.98465
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 2.96705
NOX3 NADPH oxidase 3 2.9523
IL1A interleukin 1, alpha 2.9511
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.94065
IFNA1 interferon, alpha 1 2.9322
GPR6 G protein-coupled receptor 6 2.9292
POLR1B polymerase (RNA) I polypeptide B, 128kDa 2.92602
FAM135A family with sequence similarity 135, member A 2.9222
KRT83 keratin 83, type II 2.914
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.90503
RBMY1J RNA binding motif protein, Y-linked, family 1, member J 2.90435
OR1E1 olfactory receptor, family 1, subfamily E, member 1 2.90145
CCNF cyclin F 2.90112
ATXN3L ataxin 3-like 2.8998
SLITRK3 SLIT and NTRK-like family, member 3 2.8848
PF4V1 platelet factor 4 variant 1 2.8805
SLC7A4 solute carrier family 7, member 4 2.87705
MYO3A myosin IIIA 2.8738
CBLIF cobalamin binding intrinsic factor 2.86915
TSBP1 testis expressed basic protein 1 2.86475
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.85455
LCOR ligand dependent nuclear receptor corepressor 2.8514
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 2.84695
UTS2 urotensin 2 2.8469
GYS2 glycogen synthase 2 (liver) 2.84015
TEX12 testis expressed 12 2.8394
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.83815
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.8356
IL12B interleukin 12B 2.8352
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.83465
PLP1 proteolipid protein 1 2.83145
OR2F2 olfactory receptor, family 2, subfamily F, member 2 2.81962
MROH9 maestro heat-like repeat family member 9 2.8181
HOXB8 homeobox B8 2.81735
CRYZL1 crystallin, zeta (quinone reductase)-like 1 2.81415
ZNF214 zinc finger protein 214 2.813
KRTAP5-3 keratin associated protein 5-3 2.8121
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 2.8093
PAPOLB poly(A) polymerase beta (testis specific) 2.8087
EPHA3 EPH receptor A3 2.80652
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.80065
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.79035
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.78788
OR7A17 olfactory receptor, family 7, subfamily A, member 17 2.78685
BUB1B-PAK6 BUB1B-PAK6 readthrough 2.7841
AURKB aurora kinase B 2.7832
ACR acrosin 2.78295
DGKB diacylglycerol kinase, beta 90kDa 2.7824
HMGA2 high mobility group AT-hook 2 2.77705
BRDT bromodomain, testis-specific 2.77655
CNTNAP3B contactin associated protein-like 3B 2.76055
MFAP5 microfibrillar associated protein 5 2.75562
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.752
FEZF2 FEZ family zinc finger 2 2.75145
COG4 component of oligomeric golgi complex 4 2.7504
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.7488
NSUN7 NOP2/Sun domain family, member 7 2.7479
PGAM4 phosphoglycerate mutase family member 4 2.7462
PYHIN1 pyrin and HIN domain family, member 1 2.7445
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.7365
AKAP3 A kinase (PRKA) anchor protein 3 2.7326
MOK MOK protein kinase 2.73095
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 2.72705
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 2.7219
GAS7 growth arrest-specific 7 2.72138
TBCEL tubulin folding cofactor E-like 2.71965
MLNR motilin receptor 2.7196
KIF24 kinesin family member 24 2.71445
PBOV1 prostate and breast cancer overexpressed 1 2.71405
KERA keratocan 2.7107
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.7085
CFAP68 cilia and flagella associated protein 68 2.7081
ZFY zinc finger protein, Y-linked 2.70135
MEST mesoderm specific transcript 2.70045
KNL1 kinetochore scaffold 1 2.6967
VPREB1 pre-B lymphocyte 1 2.6949
COL6A2 collagen, type VI, alpha 2 2.6945
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 2.69415
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 2.68698
IMPG1 interphotoreceptor matrix proteoglycan 1 2.6763
SV2C synaptic vesicle glycoprotein 2C 2.67325
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 2.672
SBSPON somatomedin B and thrombospondin, type 1 domain containing 2.6719
JADE2 jade family PHD finger 2 2.66985
PRDM5 PR domain containing 5 2.66705
NRDE2 NRDE-2, necessary for RNA interference, domain containing 2.6611
ADAM29 ADAM metallopeptidase domain 29 2.65345
CXCR2 chemokine (C-X-C motif) receptor 2 2.6526
OR11A1 olfactory receptor, family 11, subfamily A, member 1 2.6524
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 2.65225
LDHAL6B lactate dehydrogenase A-like 6B 2.6515
SH3PXD2A SH3 and PX domains 2A 2.64805
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.64805
IFNA8 interferon, alpha 8 2.6446
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2.64315
SNTG2 syntrophin, gamma 2 2.64225
RPGRIP1L RPGRIP1-like 2.6422
TAS2R7 taste receptor, type 2, member 7 2.63605
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.63455
RFPL1 ret finger protein-like 1 2.63345
FCAR Fc fragment of IgA receptor 2.63151
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 2.63105
TSHB thyroid stimulating hormone, beta 2.62715
CAMKV CaM kinase-like vesicle-associated 2.62675
OR2W1 olfactory receptor, family 2, subfamily W, member 1 2.6262
ZNF391 zinc finger protein 391 2.6261
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2 2.61475
BTG4 B-cell translocation gene 4 2.6137
PPIAL4H peptidylprolyl isomerase A like 4H 2.6116
MAGEB3 melanoma antigen family B3 2.60975
CMKLR2 chemerin chemokine-like receptor 2 2.6089
GPR3 G protein-coupled receptor 3 2.6062
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 2.60528
OR7A10 olfactory receptor, family 7, subfamily A, member 10 2.6044
SYN2 synapsin II 2.60192
TFF2 trefoil factor 2 2.60175
CRYGB crystallin, gamma B 2.60095
FSHR follicle stimulating hormone receptor 2.6006
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.59643
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.5951
ZNF225 zinc finger protein 225 2.58965
KRTAP9-9 keratin associated protein 9-9 2.5867
FBLN2 fibulin 2 2.57905
GUCA1B guanylate cyclase activator 1B (retina) 2.57645
CCDC144A coiled-coil domain containing 144A 2.57555
CCNJ cyclin J 2.57175
SIRT3 sirtuin 3 2.57115
THBS4 thrombospondin 4 2.56765
CPT1A carnitine palmitoyltransferase 1A (liver) 2.56696
CDH20 cadherin 20, type 2 2.5669
FYN FYN proto-oncogene, Src family tyrosine kinase 2.5656
ASTN1 astrotactin 1 2.5656
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.56545
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.56315
PCDH11X protocadherin 11 X-linked 2.5613
CYSLTR1 cysteinyl leukotriene receptor 1 2.5601
MTRF1L mitochondrial translational release factor 1-like 2.55925
MTMR10 myotubularin related protein 10 2.5558
GRM7 glutamate receptor, metabotropic 7 2.55202
LOC100996750 keratin-associated protein 4-7 2.55085
ZBTB33 zinc finger and BTB domain containing 33 2.5502
GPR88 G protein-coupled receptor 88 2.5477
XPO1 exportin 1 2.5425
DNM1L dynamin 1-like 2.54235
MLANA melan-A 2.54085
POU1F1 POU class 1 homeobox 1 2.53925
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.53885
ZNF254 zinc finger protein 254 2.53545
LOC102725023 killer cell immunoglobulin-like receptor 2DS3 allele 0020101 2.53435
SYCP1 synaptonemal complex protein 1 2.53183
PITPNM3 PITPNM family member 3 2.52855
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 2.52693
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.5249
CNTN5 contactin 5 2.5226
LGALS13 lectin, galactoside-binding, soluble, 13 2.52085
DAZ2 deleted in azoospermia 2 2.52031
RCVRN recoverin 2.5192
MYT1L myelin transcription factor 1-like 2.5107
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.49587
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.4921
IFNW1 interferon, omega 1 2.489
DCC DCC netrin 1 receptor 2.4865
RDH16 retinol dehydrogenase 16 (all-trans) 2.48575
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.48375
PCDHB8 protocadherin beta 8 2.4773
GPR85 G protein-coupled receptor 85 2.47395
ZNF80 zinc finger protein 80 2.47025
MORC1 MORC family CW-type zinc finger 1 2.46785
TSGA10 testis specific, 10 2.4667
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.46535
BSN bassoon presynaptic cytomatrix protein 2.46415
SPICE1 spindle and centriole associated protein 1 2.4626
CLDN14 claudin 14 2.45915
HOXA3 homeobox A3 2.4579
USP29 ubiquitin specific peptidase 29 2.4576
CFAP43 cilia and flagella associated protein 43 2.4541
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.45345
AANAT aralkylamine N-acetyltransferase 2.45015
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.44515
GNRHR gonadotropin-releasing hormone receptor 2.44052
SELE selectin E 2.4402
ZNF613 zinc finger protein 613 2.43495
SMR3A submaxillary gland androgen regulated protein 3A 2.4349
OR10H2 olfactory receptor, family 10, subfamily H, member 2 2.4334
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.43335
PLCH1 phospholipase C, eta 1 2.43313
ADAM2 ADAM metallopeptidase domain 2 2.4329
GAN gigaxonin 2.4315
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.4295
ANO1 anoctamin 1, calcium activated chloride channel 2.42885
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.42875
CCL7 chemokine (C-C motif) ligand 7 2.4273
ANO3 anoctamin 3 2.4248
AEBP1 AE binding protein 1 2.4235
TULP2 tubby like protein 2 2.4229
SPANXB1 SPANX family, member B1 2.4212
UBQLN3 ubiquilin 3 2.421
BCO1 beta-carotene oxygenase 1 2.4145
VCPKMT valosin containing protein lysine (K) methyltransferase 2.41315
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.41105
OR3A2 olfactory receptor, family 3, subfamily A, member 2 2.4104
CXCL6 chemokine (C-X-C motif) ligand 6 2.4101
CTAG2 cancer/testis antigen 2 2.40938
GRK4 G protein-coupled receptor kinase 4 2.40687
SH3D19 SH3 domain containing 19 2.40445
DBN1 drebrin 1 2.404
ADRA1A adrenoceptor alpha 1A 2.40359
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 2.40003
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 2.398
OR2J2 olfactory receptor, family 2, subfamily J, member 2 2.3975
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.39735
DPT dermatopontin 2.39668
FETUB fetuin B 2.3959
DNTT DNA nucleotidylexotransferase 2.3959
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 2.3945
GABPA GA binding protein transcription factor, alpha subunit 60kDa 2.3935
PENK proenkephalin 2.39315
ZFP91 ZFP91 zinc finger protein 2.39275
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 2.39097
INHBA inhibin, beta A 2.39087
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.3885
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.38655
DRD1 dopamine receptor D1 2.38375
BTN1A1 butyrophilin, subfamily 1, member A1 2.3837
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.3833
PPP4R1 protein phosphatase 4, regulatory subunit 1 2.38145
GCM1 glial cells missing homolog 1 (Drosophila) 2.3799
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 2.3797
PRAME preferentially expressed antigen in melanoma 2.37745
MERTK MER proto-oncogene, tyrosine kinase 2.37722
GCM2 glial cells missing homolog 2 (Drosophila) 2.3756
CCDC88C coiled-coil domain containing 88C 2.37515
SCUBE2 signal peptide, CUB domain, EGF-like 2 2.37505
ZNF471 zinc finger protein 471 2.3733
ETNK2 ethanolamine kinase 2 2.37195
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.3694
GLRA3 glycine receptor, alpha 3 2.36557
NPY4R2 neuropeptide Y receptor Y4-2 2.3654
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.36465
HSPA2 heat shock 70kDa protein 2 2.3638
MBNL1 muscleblind-like splicing regulator 1 2.36298
SBNO1 strawberry notch homolog 1 (Drosophila) 2.36205
ZPBP zona pellucida binding protein 2.3614
VSNL1 visinin-like 1 2.35672
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 2.35497
CABP5 calcium binding protein 5 2.35115
PTTG2 pituitary tumor-transforming 2 2.35085
FABP7 fatty acid binding protein 7, brain 2.34997
AMELX amelogenin, X-linked 2.34945
COMP cartilage oligomeric matrix protein 2.34925
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.34725
ASIC2 acid sensing (proton gated) ion channel 2 2.34565
MGAM2 maltase-glucoamylase 2 (putative) 2.34505
BMP15 bone morphogenetic protein 15 2.3431
MTMR7 myotubularin related protein 7 2.3387
ADCY10 adenylate cyclase 10 (soluble) 2.33667
ZNF780B zinc finger protein 780B 2.33615
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 2.33355
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 2.33315
PPP4R3A protein phosphatase 4 regulatory subunit 3A 2.32875
ZNF81 zinc finger protein 81 2.32785
IL12A interleukin 12A 2.3276
SIX6 SIX homeobox 6 2.3234
CUX2 cut-like homeobox 2 2.3231
VAV1 vav 1 guanine nucleotide exchange factor 2.3223
TNIP1 TNFAIP3 interacting protein 1 2.3219
F9 coagulation factor IX 2.3201
ZNF674 zinc finger protein 674 2.3176
FAM13C family with sequence similarity 13, member C 2.3167
PTGIS prostaglandin I2 (prostacyclin) synthase 2.31477
ACOXL acyl-CoA oxidase-like 2.31345
MUC6 mucin 6, oligomeric mucus/gel-forming 2.3128
MAGEL2 melanoma antigen family L2 2.31255
GPC5 glypican 5 2.31245
KDM4D lysine (K)-specific demethylase 4D 2.31145
FBXO22 F-box protein 22 2.3109
OR2B2 olfactory receptor, family 2, subfamily B, member 2 2.3085
TNN tenascin N 2.3073
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.3069
ATF7IP2 activating transcription factor 7 interacting protein 2 2.3044
GRM2 glutamate receptor, metabotropic 2 2.29975
FRRS1L ferric-chelate reductase 1-like 2.2992
BTBD8 BTB (POZ) domain containing 8 2.29865
ZNF208 zinc finger protein 208 2.29005
TSSK1B testis-specific serine kinase 1B 2.28865
TAAR2 trace amine associated receptor 2 2.28815
GRM5 glutamate receptor, metabotropic 5 2.28807
CCL11 chemokine (C-C motif) ligand 11 2.2864
LHCGR luteinizing hormone/choriogonadotropin receptor 2.28525
FAM76A family with sequence similarity 76, member A 2.28365
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.28172
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 2.2812
TRIM49B tripartite motif containing 49B 2.2778
TRAPPC8 trafficking protein particle complex 8 2.27685
DNAH2 dynein, axonemal, heavy chain 2 2.27655
TSPAN2 tetraspanin 2 2.2762
FGF7 fibroblast growth factor 7 2.2753
TNIP3 TNFAIP3 interacting protein 3 2.27495
ECHDC1 ethylmalonyl-CoA decarboxylase 1 2.2721
ZNF157 zinc finger protein 157 2.27095
KRT12 keratin 12, type I 2.2684
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.26528
ENTREP2 endosomal transmembrane epsin interactor 2 2.2646
NRIP3 nuclear receptor interacting protein 3 2.26425
MYO16 myosin XVI 2.264
MDM4 MDM4, p53 regulator 2.26195
CD8B CD8b molecule 2.26035
KIF26B kinesin family member 26B 2.2552
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.25205
STEAP1 six transmembrane epithelial antigen of the prostate 1 2.251
GPR75 G protein-coupled receptor 75 2.2502
POLR1F RNA polymerase I subunit F 2.2502
CXCL3 chemokine (C-X-C motif) ligand 3 2.24835
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 2.24745
PAX3 paired box 3 2.24617
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 2.24615
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 2.24555
RERGL RERG/RAS-like 2.24495
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 2.2445
KRTAP1-3 keratin associated protein 1-3 2.24175
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 2.2384
ELOA2 elongin A2 2.23835
WNT2B wingless-type MMTV integration site family, member 2B 2.237
AFF3 AF4/FMR2 family, member 3 2.23572
CYB5R2 cytochrome b5 reductase 2 2.23425
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.2324
TRIM49D2 tripartite motif containing 49D2 2.2311
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 2.23075
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.22935
DIAPH3 diaphanous-related formin 3 2.2292
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.2266
ZNF440 zinc finger protein 440 2.22545
KLRC4 killer cell lectin-like receptor subfamily C, member 4 2.22455
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.22455
LRRC15 leucine rich repeat containing 15 2.22215
CALB1 calbindin 1, 28kDa 2.2202
RASAL1 RAS protein activator like 1 (GAP1 like) 2.2199
RNF32 ring finger protein 32 2.2182
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.2162
MSTN myostatin 2.21595
FAM168B family with sequence similarity 168, member B 2.21445
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.2101
IFNA7 interferon, alpha 7 2.2097
LIPC lipase, hepatic 2.2093
TSKS testis-specific serine kinase substrate 2.20903
RLIM ring finger protein, LIM domain interacting 2.20535
ROPN1B rhophilin associated tail protein 1B 2.20315
ZNF835 zinc finger protein 835 2.20245
SNX16 sorting nexin 16 2.20245
SOX30 SRY (sex determining region Y)-box 30 2.20235
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.201
ZNF407 zinc finger protein 407 2.20015
MUC4 mucin 4, cell surface associated 2.19907
HRH4 histamine receptor H4 2.19745
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.19595
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.1956
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.19525
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 2.19513
PKD2L2 polycystic kidney disease 2-like 2 2.195
CLUL1 clusterin-like 1 (retinal) 2.1925
EPM2AIP1 EPM2A (laforin) interacting protein 1 2.1914
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 2.1869
GDF10 growth differentiation factor 10 2.18515
WDFY3 WD repeat and FYVE domain containing 3 2.18368
IFNA21 interferon, alpha 21 2.1821
MTUS2 microtubule associated tumor suppressor candidate 2 2.1818
GET1 guided entry of tail-anchored proteins factor 1 2.1816
PKDREJ polycystin (PKD) family receptor for egg jelly 2.1808
CATSPERB catsper channel auxiliary subunit beta 2.1803
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.18017
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.17835
TCP11 t-complex 11, testis-specific 2.1783
PLS1 plastin 1 2.17805
ADGRE3 adhesion G protein-coupled receptor E3 2.17695
KRTAP2-3 keratin associated protein 2-3 2.1754
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.17515
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.1746
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2.17415
JMJD1C jumonji domain containing 1C 2.1739
OR10J1 olfactory receptor, family 10, subfamily J, member 1 2.17115
IL26 interleukin 26 2.1703
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.16465
TCHH trichohyalin 2.16305
PDZRN4 PDZ domain containing ring finger 4 2.16235
IFNA5 interferon, alpha 5 2.15945
IFNA2 interferon, alpha 2 2.1578
RGSL1 regulator of G-protein signaling like 1 2.15695
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.15615
USP53 ubiquitin specific peptidase 53 2.156
PGK2 phosphoglycerate kinase 2 2.1512
GP6 glycoprotein VI (platelet) 2.15065
NKX2-5 NK2 homeobox 5 2.15035
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 2.14895
PLCE1 phospholipase C, epsilon 1 2.14885
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.14865
IL3RA interleukin 3 receptor, alpha (low affinity) 2.14705
GPR25 G protein-coupled receptor 25 2.14625
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.1452
CYRIA CYFIP related Rac1 interactor A 2.14477
DUOX2 dual oxidase 2 2.1444
CXCL5 chemokine (C-X-C motif) ligand 5 2.14405
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 2.1432
LINC02854 long intergenic non-protein coding RNA 2854 2.1401
PAX1 paired box 1 2.1381
PABPC3 poly(A) binding protein, cytoplasmic 3 2.13765
PRRC2A proline-rich coiled-coil 2A 2.1369
CBR3 carbonyl reductase 3 2.13675
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.13648
ADAM18 ADAM metallopeptidase domain 18 2.13585
LAMP5 lysosomal-associated membrane protein family, member 5 2.1358
TGIF1 TGFB-induced factor homeobox 1 2.13295
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.13125
CCDC121 coiled-coil domain containing 121 2.1306
KPNA5 karyopherin alpha 5 (importin alpha 6) 2.1305
CSN1S1 casein alpha s1 2.12975
MFAP4 microfibrillar-associated protein 4 2.12935
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.1293
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.1289
CALCR calcitonin receptor 2.12875
RGS7 regulator of G-protein signaling 7 2.1278
GSC2 goosecoid homeobox 2 2.12465
IFNA16 interferon, alpha 16 2.12302
FRAS1 Fraser extracellular matrix complex subunit 1 2.1229
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.1218
LRRC32 leucine rich repeat containing 32 2.1209
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 2.1203
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.11773
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.11672
FOXD2 forkhead box D2 2.116
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 2.11375
MYB v-myb avian myeloblastosis viral oncogene homolog 2.11293
CAV1 caveolin 1, caveolae protein, 22kDa 2.10845
JCAD junctional cadherin 5 associated 2.106
GPR22 G protein-coupled receptor 22 2.10535
TAS2R13 taste receptor, type 2, member 13 2.10445
OR1A2 olfactory receptor, family 1, subfamily A, member 2 2.1039
ZNF334 zinc finger protein 334 2.10255
COL14A1 collagen, type XIV, alpha 1 2.10148
MC5R melanocortin 5 receptor 2.1009
DCT dopachrome tautomerase 2.10031
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 2.09835
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 2.09798
IRAK3 interleukin-1 receptor-associated kinase 3 2.0967
CHRM5 cholinergic receptor, muscarinic 5 2.09515
TACR3 tachykinin receptor 3 2.09495
CDKL5 cyclin-dependent kinase-like 5 2.09347
S1PR5 sphingosine-1-phosphate receptor 5 2.09295
SPACA1 sperm acrosome associated 1 2.09135
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.09072
VCAN versican 2.08887
NPVF neuropeptide VF precursor 2.0882
MACIR macrophage immunometabolism regulator 2.08795
ENOPH1 enolase-phosphatase 1 2.08735
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 2.0869
HSPA13 heat shock protein 70kDa family, member 13 2.0865
OMD osteomodulin 2.08448
MMP3 matrix metallopeptidase 3 2.0843
CCDC33 coiled-coil domain containing 33 2.08395
CHN1 chimerin 1 2.0831
LRRC36 leucine rich repeat containing 36 2.0823
RTN4 reticulon 4 2.07673
RGS14 regulator of G-protein signaling 14 2.0724
THAP9 THAP domain containing 9 2.07235
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 2.07
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.06852
RAB28 RAB28, member RAS oncogene family 2.06843
GRIK3 glutamate receptor, ionotropic, kainate 3 2.0669
MAB21L4 mab-21 like 4 2.0663
CCT8 chaperonin containing TCP1, subunit 8 (theta) 2.0656
IL19 interleukin 19 2.06555
SPATA1 spermatogenesis associated 1 2.064
CHD6 chromodomain helicase DNA binding protein 6 2.06355
SIGLEC8 sialic acid binding Ig-like lectin 8 2.06325
PTPRB protein tyrosine phosphatase, receptor type, B 2.06275
RORB RAR-related orphan receptor B 2.0617
INA internexin neuronal intermediate filament protein, alpha 2.0614
STMN2 stathmin 2 2.0602
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 2.05965
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 2.05853
CCNP cyclin P 2.05745
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.0574
RYR2 ryanodine receptor 2 (cardiac) 2.05733
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 2.05725
GUCY2F guanylate cyclase 2F, retinal 2.05635
FRYL FRY-like 2.05552
GHSR growth hormone secretagogue receptor 2.0546
SLC25A30 solute carrier family 25, member 30 2.05425
FMOD fibromodulin 2.0528
EPHX3 epoxide hydrolase 3 2.052
ALOX12 arachidonate 12-lipoxygenase 2.05105
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.0491
BPY2B basic charge, Y-linked, 2B 2.046
YPEL1 yippee-like 1 (Drosophila) 2.0452
RTEL1 regulator of telomere elongation helicase 1 2.04457
SPTBN2 spectrin, beta, non-erythrocytic 2 2.04415
NXF3 nuclear RNA export factor 3 2.0413
NMBR neuromedin B receptor 2.041
PON1 paraoxonase 1 2.0403
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 2.03985
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 2.03965
CATSPERZ catsper channel auxiliary subunit zeta 2.0395
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.03875
HCFC1 host cell factor C1 2.03758
DNAAF11 dynein axonemal assembly factor 11 2.036
LSP1 lymphocyte-specific protein 1 2.03585
PPP4R4 protein phosphatase 4, regulatory subunit 4 2.03555
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.03475
OLFML3 olfactomedin-like 3 2.0347
PCSK5 proprotein convertase subtilisin/kexin type 5 2.03437
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.0338
FTSJ3 FtsJ homolog 3 (E. coli) 2.03335
PCSK2 proprotein convertase subtilisin/kexin type 2 2.0332
TTC21B tetratricopeptide repeat domain 21B 2.03275
AGBL3 ATP/GTP binding protein-like 3 2.03205
PTGDR prostaglandin D2 receptor (DP) 2.0316
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough 2.02925
MMP27 matrix metallopeptidase 27 2.02825
TIGD6 tigger transposable element derived 6 2.0279
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 2.02688
DMRT1 doublesex and mab-3 related transcription factor 1 2.02665
SAGE1 sarcoma antigen 1 2.0261
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 2.02535
CCL23 chemokine (C-C motif) ligand 23 2.0249
MRPS17 mitochondrial ribosomal protein S17 2.02355
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.0226
ZNF493 zinc finger protein 493 2.02255
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.0204
FASTKD5 FAST kinase domains 5 2.02005
DRD3 dopamine receptor D3 2.0197
ARL14 ADP-ribosylation factor-like 14 2.0195
PTPRT protein tyrosine phosphatase, receptor type, T 2.01695
SRY sex determining region Y 2.0136
PRRX1 paired related homeobox 1 2.01355
SPRED2 sprouty-related, EVH1 domain containing 2 2.0126
KRT35 keratin 35, type I 2.012
ADGB androglobin 2.012
CYSLTR2 cysteinyl leukotriene receptor 2 2.0117
AJAP1 adherens junctions associated protein 1 2.01143
HARS1 histidyl-tRNA synthetase 1 2.0107
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 2.00945
H2BC11 H2B clustered histone 11 2.0094
LATS1 large tumor suppressor kinase 1 2.00605
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.00585
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 2.00577
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 2.00445
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.00327
DAAM2 dishevelled associated activator of morphogenesis 2 2.003
FRMPD4 FERM and PDZ domain containing 4 2.00295
PEX5L peroxisomal biogenesis factor 5-like 2.0024

decreased expression

Symbol Name Standardized Value
NT5DC2 5'-nucleotidase domain containing 2 -9.5264
CCNB2 cyclin B2 -8.9447
MRPS2 mitochondrial ribosomal protein S2 -5.61765
FBXL12 F-box and leucine-rich repeat protein 12 -5.54935
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -5.29225
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.8596
NUP85 nucleoporin 85kDa -4.8391
THAP11 THAP domain containing 11 -4.8217
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.67805
USP6NL USP6 N-terminal like -4.46245
NGRN neugrin, neurite outgrowth associated -4.364
ARID5B AT rich interactive domain 5B (MRF1-like) -4.1367
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -4.10545
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.92355
KIF14 kinesin family member 14 -3.87355
TLCD3A TLC domain containing 3A -3.8245
PPP1R26 protein phosphatase 1, regulatory subunit 26 -3.74605
GRWD1 glutamate-rich WD repeat containing 1 -3.6167
YME1L1 YME1-like 1 ATPase -3.59852
ARHGAP1 Rho GTPase activating protein 1 -3.58205
WDR7 WD repeat domain 7 -3.42225
CUTA cutA divalent cation tolerance homolog (E. coli) -3.39345
TOMM34 translocase of outer mitochondrial membrane 34 -3.36395
GNAS GNAS complex locus -3.33595
TCTN1 tectonic family member 1 -3.3315
SOX9 SRY (sex determining region Y)-box 9 -3.31247
CRTAP cartilage associated protein -3.2207
MRPL58 mitochondrial ribosomal protein L58 -3.1714
MCM3 minichromosome maintenance complex component 3 -3.1377
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -3.09745
ANAPC2 anaphase promoting complex subunit 2 -3.01695
CHIC2 cysteine-rich hydrophobic domain 2 -2.9885
BLMH bleomycin hydrolase -2.9803
TRAPPC3 trafficking protein particle complex 3 -2.97762
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.88401
CAB39 calcium binding protein 39 -2.87815
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -2.8602
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.7739
KCTD2 potassium channel tetramerization domain containing 2 -2.7592
CDKN2A cyclin-dependent kinase inhibitor 2A -2.75717
BTBD1 BTB (POZ) domain containing 1 -2.7549
MAP2K5 mitogen-activated protein kinase kinase 5 -2.72247
INTS9 integrator complex subunit 9 -2.673
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.66855
GET3 guided entry of tail-anchored proteins factor 3, ATPase -2.65545
RPIA ribose 5-phosphate isomerase A -2.6468
RBBP5 retinoblastoma binding protein 5 -2.64095
CHMP7 charged multivesicular body protein 7 -2.62135
CD58 CD58 molecule -2.60867
PANK4 pantothenate kinase 4 -2.60265
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.59615
SNX11 sorting nexin 11 -2.55262
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.53115
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.5311
TMEM184C transmembrane protein 184C -2.52635
NXN nucleoredoxin -2.4845
PCBP4 poly(rC) binding protein 4 -2.479
UBE3C ubiquitin protein ligase E3C -2.45125
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.3937
IER2 immediate early response 2 -2.38945
GTPBP8 GTP-binding protein 8 (putative) -2.3722
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.36735
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -2.34945
JUN jun proto-oncogene -2.34943
DET1 de-etiolated homolog 1 (Arabidopsis) -2.34545
CCDC85B coiled-coil domain containing 85B -2.3423
FABP3 fatty acid binding protein 3, muscle and heart -2.33735
RNASEH2A ribonuclease H2, subunit A -2.33608
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -2.33275
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -2.3279
NELFB negative elongation factor complex member B -2.29175
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -2.27915
CRYL1 crystallin, lambda 1 -2.25805
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) -2.2541
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.25235
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -2.2478
GRB7 growth factor receptor-bound protein 7 -2.2433
LMO1 LIM domain only 1 (rhombotin 1) -2.23765
DCTN3 dynactin 3 (p22) -2.2361
GTF2IRD1 GTF2I repeat domain containing 1 -2.23075
ZNF586 zinc finger protein 586 -2.22875
ZCCHC2 zinc finger, CCHC domain containing 2 -2.22695
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 -2.22555
NCK2 NCK adaptor protein 2 -2.2205
PROSER1 proline and serine rich 1 -2.20745
AUNIP aurora kinase A and ninein interacting protein -2.20395
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.2021
STX16 syntaxin 16 -2.1941
WFDC1 WAP four-disulfide core domain 1 -2.17355
ZNF91 zinc finger protein 91 -2.1694
ZNF430 zinc finger protein 430 -2.167
FJX1 four jointed box 1 (Drosophila) -2.1605
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -2.1487
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.1451
KLHL21 kelch-like family member 21 -2.14415
BRD3OS BRD3 opposite strand -2.14035
RNF111 ring finger protein 111 -2.14
MPHOSPH8 M-phase phosphoprotein 8 -2.135
OBP2B odorant binding protein 2B -2.12975
CDR2L cerebellar degeneration-related protein 2-like -2.1263
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -2.11615
SPAG4 sperm associated antigen 4 -2.11335
COPG1 coatomer protein complex, subunit gamma 1 -2.11115
RNF113A ring finger protein 113A -2.10365
IPP intracisternal A particle-promoted polypeptide -2.1032
REPIN1 replication initiator 1 -2.0995
CLEC16A C-type lectin domain family 16, member A -2.09895
LOC128966622 putative protein N-methyltransferase FAM86B2 -2.0892
MPO myeloperoxidase -2.08777
GATAD1 GATA zinc finger domain containing 1 -2.08052
CHAMP1 chromosome alignment maintaining phosphoprotein 1 -2.07985
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.0771
EPPK1 epiplakin 1 -2.0659
ATP5PD ATP synthase peripheral stalk subunit d -2.06495
AKIP1 A kinase (PRKA) interacting protein 1 -2.0558
EIF2D eukaryotic translation initiation factor 2D -2.05065
RETN resistin -2.047
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.03835
PMM2 phosphomannomutase 2 -2.0369
RFC3 replication factor C (activator 1) 3, 38kDa -2.03095
URM1 ubiquitin related modifier 1 -2.02925
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -2.02165
ZNF248 zinc finger protein 248 -2.0147
BABAM1 BRISC and BRCA1 A complex member 1 -2.0119
GRB2 growth factor receptor-bound protein 2 -2.01065