| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | furan 9.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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91 genes differentially expressed following the CRCGN011_HEPG2_24H:N03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.5622 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.5173 |
| E2F2 | E2F transcription factor 2 | 4.97705 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 4.6807 |
| STIMATE | STIM activating enhancer | 4.56585 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.4453 |
| KIF5C | kinesin family member 5C | 3.8989 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 3.85425 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.79277 |
| PFKL | phosphofructokinase, liver | 3.4332 |
| CHN1 | chimerin 1 | 3.362 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.30185 |
| ATP11B | ATPase, class VI, type 11B | 3.0518 |
| MEST | mesoderm specific transcript | 2.98915 |
| FASTKD5 | FAST kinase domains 5 | 2.79285 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.61795 |
| HMGA2 | high mobility group AT-hook 2 | 2.4826 |
| CORO1A | coronin, actin binding protein, 1A | 2.4643 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.45148 |
| PALM | paralemmin | 2.4389 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 2.41985 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.38 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 2.3726 |
| BIRC3 | baculoviral IAP repeat containing 3 | 2.3501 |
| DIPK1A | divergent protein kinase domain 1A | 2.33125 |
| GSDMB | gasdermin B | 2.3258 |
| DEPP1 | DEPP autophagy regulator 1 | 2.28293 |
| ZNF267 | zinc finger protein 267 | 2.277 |
| CDK2 | cyclin-dependent kinase 2 | 2.26345 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 2.23135 |
| SLC75A1 | solute carrier family 75 member 1 | 2.23085 |
| ICE2 | interactor of little elongation complex ELL subunit 2 | 2.23065 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 | 2.22245 |
| TMEM106C | transmembrane protein 106C | 2.2001 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 2.19255 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.13501 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.13485 |
| DRC9 | dynein regulatory complex subunit 9 | 2.1028 |
| GPR63 | G protein-coupled receptor 63 | 2.0889 |
| OSGEP | O-sialoglycoprotein endopeptidase | 2.0885 |
| TRIM15 | tripartite motif containing 15 | 2.06763 |
| IL18R1 | interleukin 18 receptor 1 | 2.06755 |
| BMPR1B | bone morphogenetic protein receptor, type IB | 2.0633 |
| HKDC1 | hexokinase domain containing 1 | 2.0349 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 2.02995 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -9.3667 |
| GNAS | GNAS complex locus | -7.38916 |
| MAPK13 | mitogen-activated protein kinase 13 | -7.03528 |
| CDC20 | cell division cycle 20 | -5.5741 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.18555 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -5.113 |
| LAP3 | leucine aminopeptidase 3 | -4.93255 |
| USP6NL | USP6 N-terminal like | -4.8571 |
| PEG10 | paternally expressed 10 | -4.8302 |
| PCNA | proliferating cell nuclear antigen | -4.82295 |
| LDHD | lactate dehydrogenase D | -4.5409 |
| TCTN1 | tectonic family member 1 | -4.2173 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -4.082 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.08015 |
| BMP4 | bone morphogenetic protein 4 | -3.81455 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.81227 |
| ADI1 | acireductone dioxygenase 1 | -3.5037 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.99498 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.92742 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.8598 |
| PRPF4 | pre-mRNA processing factor 4 | -2.77513 |
| BZW2 | basic leucine zipper and W2 domains 2 | -2.7601 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.75435 |
| POMP | proteasome maturation protein | -2.72875 |
| RNF167 | ring finger protein 167 | -2.65845 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | -2.65817 |
| HMG20B | high mobility group 20B | -2.55415 |
| XPO7 | exportin 7 | -2.45163 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.3244 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) | -2.3124 |
| S100A2 | S100 calcium binding protein A2 | -2.2158 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -2.2142 |
| MEPCE | methylphosphate capping enzyme | -2.1934 |
| NMRK1 | nicotinamide riboside kinase 1 | -2.14115 |
| HOXC10 | homeobox C10 | -2.14035 |
| NTM | neurotrimin | -2.11185 |
| GLB1L | galactosidase, beta 1-like | -2.0746 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.06555 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.06405 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -2.0492 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.0389 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -2.03525 |
| POLI | polymerase (DNA directed) iota | -2.02805 |
| WASHC4 | WASH complex subunit 4 | -2.01532 |
| SRRD | SRR1 domain containing | -2.0083 |
| TP53RK | TP53 regulating kinase | -2.0034 |
