| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | roxarsone 4.98 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
75 genes differentially expressed following the CRCGN011_HEPG2_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS3 | integrator complex subunit 3 | 5.29085 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.12175 |
| TBPL1 | TBP-like 1 | 5.05065 |
| TLR4 | toll-like receptor 4 | 4.66735 |
| UBQLN2 | ubiquilin 2 | 4.65505 |
| ATP11B | ATPase, class VI, type 11B | 4.49785 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.2769 |
| MAP7 | microtubule-associated protein 7 | 4.15538 |
| ABHD6 | abhydrolase domain containing 6 | 3.92297 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 3.8424 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.62655 |
| COL11A1 | collagen, type XI, alpha 1 | 3.60223 |
| CYCS | cytochrome c, somatic | 3.5997 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.44735 |
| EPN2 | epsin 2 | 3.44588 |
| PMM2 | phosphomannomutase 2 | 2.8782 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.57565 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | 2.4916 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.48633 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 2.47935 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.4729 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 2.43505 |
| CHN1 | chimerin 1 | 2.423 |
| EDN1 | endothelin 1 | 2.4033 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.25695 |
| NDRG4 | NDRG family member 4 | 2.24265 |
| PLSCR4 | phospholipid scramblase 4 | 2.23285 |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 | 2.2146 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 2.2067 |
| GPM6A | glycoprotein M6A | 2.1623 |
| KIAA0319L | KIAA0319-like | 2.1279 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 | 2.12025 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.09242 |
| PROX1 | prospero homeobox 1 | 2.05395 |
| EXOSC5 | exosome component 5 | 2.0359 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 2.02932 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | 2.0203 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | 2.01665 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 2.01447 |
| KCNJ9 | potassium channel, inwardly rectifying subfamily J, member 9 | 2.01175 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 2.0111 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.49935 |
| GDF15 | growth differentiation factor 15 | -6.5296 |
| CDK4 | cyclin-dependent kinase 4 | -5.7679 |
| HSPB1 | heat shock 27kDa protein 1 | -5.3468 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.28605 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.1417 |
| VAT1 | vesicle amine transport 1 | -4.92445 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.8902 |
| TSPAN4 | tetraspanin 4 | -4.80443 |
| PCNA | proliferating cell nuclear antigen | -4.7455 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.71785 |
| LDHD | lactate dehydrogenase D | -4.6773 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.61425 |
| ADI1 | acireductone dioxygenase 1 | -4.474 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.35985 |
| SLC35F2 | solute carrier family 35, member F2 | -3.9201 |
| TLCD3A | TLC domain containing 3A | -3.64735 |
| TES | testin LIM domain protein | -3.5307 |
| GNAS | GNAS complex locus | -3.43596 |
| MTFR1 | mitochondrial fission regulator 1 | -3.30542 |
| HMG20B | high mobility group 20B | -2.51055 |
| CAPN1 | calpain 1, (mu/I) large subunit | -2.50825 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.5044 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.3355 |
| EEF1AKMT3 | EEF1A lysine methyltransferase 3 | -2.3239 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | -2.27595 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) | -2.2551 |
| MYO5C | myosin VC | -2.18115 |
| ESYT1 | extended synaptotagmin-like protein 1 | -2.12445 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.12172 |
| PDZD2 | PDZ domain containing 2 | -2.10468 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | -2.0932 |
| BIRC7 | baculoviral IAP repeat containing 7 | -2.07985 |
| CCNG2 | cyclin G2 | -2.00972 |
