CRCGN011_HEPG2_24H:N11 Gene Set
Genes
45 genes differentially expressed following the CRCGN011_HEPG2_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.84142
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.4297
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
5.12978
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.02315
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.824
|
|
TLR4
|
toll-like receptor 4
|
4.61865
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.09828
|
|
STIMATE
|
STIM activating enhancer
|
3.6159
|
|
EVL
|
Enah/Vasp-like
|
3.5242
|
|
COQ8A
|
coenzyme Q8A
|
3.0653
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.00015
|
|
TRAK2
|
trafficking protein, kinesin binding 2
|
2.7781
|
|
CCNA1
|
cyclin A1
|
2.6529
|
|
CHN1
|
chimerin 1
|
2.6034
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.5606
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.43767
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.40202
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.3664
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.3033
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.21457
|
|
CBR3
|
carbonyl reductase 3
|
2.208
|
|
RYR1
|
ryanodine receptor 1 (skeletal)
|
2.06035
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-7.6458
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-5.1742
|
|
VAT1
|
vesicle amine transport 1
|
-4.5458
|
|
PLK1
|
polo-like kinase 1
|
-4.2397
|
|
GNAS
|
GNAS complex locus
|
-3.50323
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-3.45195
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.32285
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.2973
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-3.18337
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.0844
|
|
CCNB2
|
cyclin B2
|
-3.06365
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.6893
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.5353
|
|
GTF2A1
|
general transcription factor IIA, 1, 19/37kDa
|
-2.4398
|
|
LGMN
|
legumain
|
-2.38045
|
|
CLDN4
|
claudin 4
|
-2.2517
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.23618
|
|
CDC25B
|
cell division cycle 25B
|
-2.22
|
|
PRICKLE3
|
prickle homolog 3 (Drosophila)
|
-2.20035
|
|
RPUSD2
|
RNA pseudouridylate synthase domain containing 2
|
-2.18075
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.13705
|
|
PTGES3
|
prostaglandin E synthase 3 (cytosolic)
|
-2.12315
|
|
CDKN2B
|
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
|
-2.1116
|
