| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | roxarsone 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN011_HEPG2_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PNKP | polynucleotide kinase 3'-phosphatase | 5.2837 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.9859 |
| STK10 | serine/threonine kinase 10 | 4.928 |
| UBQLN2 | ubiquilin 2 | 4.8205 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.7064 |
| MAMLD1 | mastermind-like domain containing 1 | 4.66625 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.66275 |
| NOTCH1 | notch 1 | 4.47565 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.96455 |
| PRKCH | protein kinase C, eta | 3.44585 |
| GPATCH8 | G patch domain containing 8 | 3.23628 |
| KLHL9 | kelch-like family member 9 | 3.0731 |
| ZNF26 | zinc finger protein 26 | 2.89795 |
| PRR15L | proline rich 15-like | 2.8714 |
| CCNA1 | cyclin A1 | 2.8211 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 2.3372 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.33075 |
| ZNF589 | zinc finger protein 589 | 2.30843 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.30582 |
| TMEM242 | transmembrane protein 242 | 2.2743 |
| PPA2 | pyrophosphatase (inorganic) 2 | 2.2231 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.19381 |
| HSPA1A | heat shock 70kDa protein 1A | 2.17235 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 2.154 |
| NUP37 | nucleoporin 37kDa | 2.11705 |
| UPK1B | uroplakin 1B | 2.096 |
| TCIM | transcriptional and immune response regulator | 2.0853 |
| EIF2B1 | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 2.0592 |
| LBHD1 | LBH domain containing 1 | 2.0501 |
| FASTKD5 | FAST kinase domains 5 | 2.0231 |
| IFT52 | intraflagellar transport 52 | 2.01235 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.0037 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 2.0034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.83625 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -5.35145 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.29885 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.8871 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.78965 |
| CD320 | CD320 molecule | -4.69355 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.6132 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.3861 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.83 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.59448 |
| DSG2 | desmoglein 2 | -3.34305 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -3.042 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.0052 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.78433 |
| PRPF4 | pre-mRNA processing factor 4 | -2.6713 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -2.6283 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.53585 |
| CCDC28A | coiled-coil domain containing 28A | -2.32725 |
| PRSS22 | protease, serine, 22 | -2.3193 |
| GRAMD4 | GRAM domain containing 4 | -2.3047 |
| CD44 | CD44 molecule (Indian blood group) | -2.19435 |
| DGCR2 | DiGeorge syndrome critical region gene 2 | -2.1888 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.18225 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -2.11715 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.11583 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | -2.07435 |
| SAMD9 | sterile alpha motif domain containing 9 | -2.05685 |
| RAB36 | RAB36, member RAS oncogene family | -2.04665 |
