| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-(4-amino-2-nitroanilino)ethanol 0.67 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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51 genes differentially expressed following the CRCGN011_HEPG2_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.50615 |
| LCN2 | lipocalin 2 | 5.0 |
| NMU | neuromedin U | 4.4873 |
| STK10 | serine/threonine kinase 10 | 4.31888 |
| MMP2 | matrix metallopeptidase 2 | 3.82035 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.62913 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 3.62655 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.53078 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.4344 |
| CYCS | cytochrome c, somatic | 3.40635 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.19515 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 3.02435 |
| JADE2 | jade family PHD finger 2 | 3.01442 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.86975 |
| TRAM2 | translocation associated membrane protein 2 | 2.76823 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.702 |
| COL11A1 | collagen, type XI, alpha 1 | 2.57157 |
| CSK | c-src tyrosine kinase | 2.53815 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.4663 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.39883 |
| UROS | uroporphyrinogen III synthase | 2.33755 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.27973 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 | 2.19965 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 | 2.19885 |
| H1-4 | H1.4 linker histone, cluster member | 2.18635 |
| COX7B | cytochrome c oxidase subunit VIIb | 2.12085 |
| CAVIN1 | caveolae associated protein 1 | 2.0482 |
| CTSB | cathepsin B | 2.03005 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.8584 |
| CCDC86 | coiled-coil domain containing 86 | -4.8161 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.80925 |
| CDC20 | cell division cycle 20 | -4.66275 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.62135 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.58838 |
| CAB39 | calcium binding protein 39 | -3.56835 |
| UBE3C | ubiquitin protein ligase E3C | -2.8956 |
| TBX2 | T-box 2 | -2.50883 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -2.48943 |
| WASHC4 | WASH complex subunit 4 | -2.27942 |
| GDF15 | growth differentiation factor 15 | -2.23645 |
| SETBP1 | SET binding protein 1 | -2.22765 |
| TCERG1 | transcription elongation regulator 1 | -2.1978 |
| VDAC1 | voltage-dependent anion channel 1 | -2.13425 |
| ZNF516 | zinc finger protein 516 | -2.10385 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide | -2.07195 |
| HSPA4L | heat shock 70kDa protein 4-like | -2.06735 |
| PGRMC1 | progesterone receptor membrane component 1 | -2.06545 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 | -2.0641 |
| APIP | APAF1 interacting protein | -2.0571 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -2.0372 |
| CENPE | centromere protein E, 312kDa | -2.0346 |
