CRCGN011_HEPG2_24H:N20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description coumophos 9.92 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

68 genes differentially expressed following the CRCGN011_HEPG2_24H:N20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 8.1159
JADE2 jade family PHD finger 2 5.85505
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.46645
CARMIL1 capping protein regulator and myosin 1 linker 1 5.2383
RPP38 ribonuclease P/MRP 38kDa subunit 5.2028
UBQLN2 ubiquilin 2 5.0082
LCN2 lipocalin 2 4.98615
CHMP6 charged multivesicular body protein 6 4.9615
PPARG peroxisome proliferator-activated receptor gamma 4.95215
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.77695
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.7178
CCDC85B coiled-coil domain containing 85B 4.3484
LOC122526780 uncharacterized LOC122526780 3.45565
NOSIP nitric oxide synthase interacting protein 3.33925
CCL2 chemokine (C-C motif) ligand 2 3.1805
KDM5A lysine (K)-specific demethylase 5A 3.03785
HLA-DRA major histocompatibility complex, class II, DR alpha 2.9443
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 2.77495
BPIFA1 BPI fold containing family A, member 1 2.55235
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.3577
FOXRED2 FAD-dependent oxidoreductase domain containing 2 2.338
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.2966
SDAD1 SDA1 domain containing 1 2.2375
SMIM10L1 small integral membrane protein 10 like 1 2.2132
TXNL4B thioredoxin-like 4B 2.13245
MSRB2 methionine sulfoxide reductase B2 2.12757
SPRING1 SREBF pathway regulator in golgi 1 2.11815
PRSS21 protease, serine, 21 (testisin) 2.1161
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.10155
COPS7A COP9 signalosome subunit 7A 2.09785
FOXM1 forkhead box M1 2.09555
TRAPPC2L trafficking protein particle complex 2-like 2.089
BANF1 barrier to autointegration factor 1 2.0644
UBFD1 ubiquitin family domain containing 1 2.03785
BANP BTG3 associated nuclear protein 2.03645
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 2.00615

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -10.0
PCNA proliferating cell nuclear antigen -8.5589
MRPS2 mitochondrial ribosomal protein S2 -5.9126
UGDH UDP-glucose 6-dehydrogenase -5.1771
TRIB3 tribbles pseudokinase 3 -5.0
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.816
GOLT1B golgi transport 1B -4.48325
CASP3 caspase 3, apoptosis-related cysteine peptidase -4.30655
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.2227
CDC20 cell division cycle 20 -4.2155
ZMIZ1 zinc finger, MIZ-type containing 1 -3.8792
TLCD3A TLC domain containing 3A -3.5929
GADD45A growth arrest and DNA-damage-inducible, alpha -3.44285
LYPLA1 lysophospholipase I -3.43985
ANKRD10 ankyrin repeat domain 10 -3.00695
MAPK13 mitogen-activated protein kinase 13 -2.8946
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.8413
RNF167 ring finger protein 167 -2.49255
RGS2 regulator of G-protein signaling 2 -2.3024
ZNF423 zinc finger protein 423 -2.27195
GBE1 glucan (1,4-alpha-), branching enzyme 1 -2.2505
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.21455
FOS FBJ murine osteosarcoma viral oncogene homolog -2.19725
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) -2.15765
SCN3A sodium channel, voltage gated, type III alpha subunit -2.1447
CA2 carbonic anhydrase II -2.1362
RECK reversion-inducing-cysteine-rich protein with kazal motifs -2.13275
EPS8L2 EPS8-like 2 -2.097
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.0743
NFASC neurofascin -2.07175
MRPL15 mitochondrial ribosomal protein L15 -2.0564
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -2.03355