| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | coumophos 9.92 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN011_HEPG2_24H:N20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 8.1159 |
| JADE2 | jade family PHD finger 2 | 5.85505 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.46645 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.2383 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.2028 |
| UBQLN2 | ubiquilin 2 | 5.0082 |
| LCN2 | lipocalin 2 | 4.98615 |
| CHMP6 | charged multivesicular body protein 6 | 4.9615 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.95215 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.77695 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.7178 |
| CCDC85B | coiled-coil domain containing 85B | 4.3484 |
| LOC122526780 | uncharacterized LOC122526780 | 3.45565 |
| NOSIP | nitric oxide synthase interacting protein | 3.33925 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.1805 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.03785 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.9443 |
| EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 | 2.77495 |
| BPIFA1 | BPI fold containing family A, member 1 | 2.55235 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.3577 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 | 2.338 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 2.2966 |
| SDAD1 | SDA1 domain containing 1 | 2.2375 |
| SMIM10L1 | small integral membrane protein 10 like 1 | 2.2132 |
| TXNL4B | thioredoxin-like 4B | 2.13245 |
| MSRB2 | methionine sulfoxide reductase B2 | 2.12757 |
| SPRING1 | SREBF pathway regulator in golgi 1 | 2.11815 |
| PRSS21 | protease, serine, 21 (testisin) | 2.1161 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 2.10155 |
| COPS7A | COP9 signalosome subunit 7A | 2.09785 |
| FOXM1 | forkhead box M1 | 2.09555 |
| TRAPPC2L | trafficking protein particle complex 2-like | 2.089 |
| BANF1 | barrier to autointegration factor 1 | 2.0644 |
| UBFD1 | ubiquitin family domain containing 1 | 2.03785 |
| BANP | BTG3 associated nuclear protein | 2.03645 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 2.00615 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| PCNA | proliferating cell nuclear antigen | -8.5589 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.9126 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.1771 |
| TRIB3 | tribbles pseudokinase 3 | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.816 |
| GOLT1B | golgi transport 1B | -4.48325 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -4.30655 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.2227 |
| CDC20 | cell division cycle 20 | -4.2155 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.8792 |
| TLCD3A | TLC domain containing 3A | -3.5929 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -3.44285 |
| LYPLA1 | lysophospholipase I | -3.43985 |
| ANKRD10 | ankyrin repeat domain 10 | -3.00695 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.8946 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.8413 |
| RNF167 | ring finger protein 167 | -2.49255 |
| RGS2 | regulator of G-protein signaling 2 | -2.3024 |
| ZNF423 | zinc finger protein 423 | -2.27195 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -2.2505 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.21455 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.19725 |
| SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | -2.15765 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -2.1447 |
| CA2 | carbonic anhydrase II | -2.1362 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | -2.13275 |
| EPS8L2 | EPS8-like 2 | -2.097 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -2.0743 |
| NFASC | neurofascin | -2.07175 |
| MRPL15 | mitochondrial ribosomal protein L15 | -2.0564 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -2.03355 |