| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | coumophos 0.62 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN011_HEPG2_24H:N24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPATCH8 | G patch domain containing 8 | 5.33763 |
| NOTCH1 | notch 1 | 5.1522 |
| BZW2 | basic leucine zipper and W2 domains 2 | 5.06755 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.76425 |
| STIMATE | STIM activating enhancer | 4.6468 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.45265 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 4.01338 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.99015 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.95805 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.8313 |
| ABHD6 | abhydrolase domain containing 6 | 3.7332 |
| TLR4 | toll-like receptor 4 | 3.66005 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 3.49355 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.389 |
| SKIC2 | SKI2 subunit of superkiller complex | 3.21705 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.11478 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.90172 |
| PIH1D1 | PIH1 domain containing 1 | 2.5234 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.4153 |
| KLHL9 | kelch-like family member 9 | 2.38293 |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa | 2.31635 |
| TMEM39A | transmembrane protein 39A | 2.3148 |
| CCNF | cyclin F | 2.30877 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.2459 |
| SLC66A2 | solute carrier family 66 member 2 | 2.21145 |
| SEPHS1 | selenophosphate synthetase 1 | 2.1667 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.1655 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.13912 |
| POP7 | processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) | 2.1381 |
| GATA2 | GATA binding protein 2 | 2.1332 |
| RHCG | Rh family, C glycoprotein | 2.11815 |
| FASTKD5 | FAST kinase domains 5 | 2.07615 |
| NOSIP | nitric oxide synthase interacting protein | 2.03955 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.038 |
| S100A8 | S100 calcium binding protein A8 | 2.0307 |
| XPO4 | exportin 4 | 2.02285 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.9455 |
| CCNB1 | cyclin B1 | -5.6923 |
| MAP7 | microtubule-associated protein 7 | -5.0141 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.75615 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.6938 |
| TRIB3 | tribbles pseudokinase 3 | -4.60435 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.5824 |
| CCDC86 | coiled-coil domain containing 86 | -4.57165 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.4854 |
| CHMP4B | charged multivesicular body protein 4B | -4.31767 |
| VAT1 | vesicle amine transport 1 | -4.2457 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.8011 |
| GNAS | GNAS complex locus | -3.59421 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.46225 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.3856 |
| PEG10 | paternally expressed 10 | -2.54822 |
| APOE | apolipoprotein E | -2.47635 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated | -2.3552 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.26947 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -2.16345 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 | -2.1497 |
| RNF167 | ring finger protein 167 | -2.1404 |
| ADAM2 | ADAM metallopeptidase domain 2 | -2.06375 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit | -2.05615 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | -2.05385 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | -2.048 |
| EFL1 | elongation factor like GTPase 1 | -2.04355 |
| AMZ2 | archaelysin family metallopeptidase 2 | -2.0194 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.01715 |
