CRCGN011_HEPG2_24H:O12 Gene Set
Genes
51 genes differentially expressed following the CRCGN011_HEPG2_24H:O12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.6466
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.53825
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
5.53605
|
|
NOTCH1
|
notch 1
|
5.05415
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.0466
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.016
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
4.3915
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.29213
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.15025
|
|
CYCS
|
cytochrome c, somatic
|
3.9632
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
3.48125
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.41775
|
|
H2BC12
|
H2B clustered histone 12
|
3.33375
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.99385
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
2.95375
|
|
PRAF2
|
PRA1 domain family, member 2
|
2.84545
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.65683
|
|
SIRT3
|
sirtuin 3
|
2.63108
|
|
ID1
|
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
|
2.609
|
|
JADE2
|
jade family PHD finger 2
|
2.59282
|
|
RNF167
|
ring finger protein 167
|
2.52235
|
|
RIC8A
|
RIC8 guanine nucleotide exchange factor A
|
2.44775
|
|
TOPORS
|
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
|
2.4446
|
|
HIVEP1
|
human immunodeficiency virus type I enhancer binding protein 1
|
2.4056
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.3922
|
|
ZNF43
|
zinc finger protein 43
|
2.23005
|
|
RIGI
|
RNA sensor RIG-I
|
2.2002
|
|
CHN1
|
chimerin 1
|
2.1977
|
|
TPSAB1
|
tryptase alpha/beta 1
|
2.07613
|
|
IFIT2
|
interferon-induced protein with tetratricopeptide repeats 2
|
2.0413
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
CCNB2
|
cyclin B2
|
-8.34655
|
|
LDHD
|
lactate dehydrogenase D
|
-4.73895
|
|
HMG20B
|
high mobility group 20B
|
-4.32807
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.29135
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.5974
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.23422
|
|
RPS5
|
ribosomal protein S5
|
-3.16095
|
|
GDF15
|
growth differentiation factor 15
|
-2.9062
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.8299
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.77895
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.41405
|
|
MYO5A
|
myosin VA (heavy chain 12, myoxin)
|
-2.4112
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.2553
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.1403
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.0449
|
|
DHRS3
|
dehydrogenase/reductase (SDR family) member 3
|
-2.03905
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-2.02695
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.02498
|
|
LOC102723713
|
TP53-target gene 3 protein
|
-2.0169
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.00555
|
