CRCGN011_HEPG2_24H:O14 Gene Set
Genes
49 genes differentially expressed following the CRCGN011_HEPG2_24H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ZNF589
|
zinc finger protein 589
|
5.67178
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.1149
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
5.1014
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.05825
|
|
STK10
|
serine/threonine kinase 10
|
4.85865
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.76525
|
|
STIMATE
|
STIM activating enhancer
|
4.74885
|
|
MYLK
|
myosin light chain kinase
|
4.6322
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.44445
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.51775
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
3.0012
|
|
CCNF
|
cyclin F
|
2.99618
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.86065
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.73145
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.69045
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.6595
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.53575
|
|
CRTAP
|
cartilage associated protein
|
2.49475
|
|
NNT
|
nicotinamide nucleotide transhydrogenase
|
2.48215
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.37892
|
|
CEP57
|
centrosomal protein 57kDa
|
2.29792
|
|
KCTD17
|
potassium channel tetramerization domain containing 17
|
2.26625
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.1848
|
|
CHAMP1
|
chromosome alignment maintaining phosphoprotein 1
|
2.0714
|
|
NTAQ1
|
N-terminal glutamine amidase 1
|
2.06385
|
|
LARS1
|
leucyl-tRNA synthetase 1
|
2.0401
|
|
EFCAB6
|
EF-hand calcium binding domain 6
|
2.0021
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-6.79345
|
|
HAT1
|
histone acetyltransferase 1
|
-5.436
|
|
GDF15
|
growth differentiation factor 15
|
-5.0
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.98075
|
|
SCAND1
|
SCAN domain containing 1
|
-4.71615
|
|
VAT1
|
vesicle amine transport 1
|
-4.45915
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.77115
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.6192
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.46422
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.4388
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.2489
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.05273
|
|
GNAS
|
GNAS complex locus
|
-2.9944
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.6639
|
|
CAB39
|
calcium binding protein 39
|
-2.16205
|
|
ASPA
|
aspartoacylase
|
-2.1555
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-2.14305
|
|
DYNC1I2
|
dynein, cytoplasmic 1, intermediate chain 2
|
-2.1333
|
|
ZDHHC13
|
zinc finger, DHHC-type containing 13
|
-2.1109
|
|
SP3
|
Sp3 transcription factor
|
-2.1072
|
|
NUAK2
|
NUAK family, SNF1-like kinase, 2
|
-2.0909
|
|
SREK1
|
splicing regulatory glutamine/lysine-rich protein 1
|
-2.07795
|
