| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tributyl phosphate 9.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN011_HEPG2_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 6.26245 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.13165 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.70055 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 4.5638 |
| KIF5C | kinesin family member 5C | 3.73618 |
| MAP7 | microtubule-associated protein 7 | 3.58645 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 3.44227 |
| KLHL9 | kelch-like family member 9 | 3.32888 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.19965 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.18418 |
| BAX | BCL2-associated X protein | 3.15425 |
| ZNF589 | zinc finger protein 589 | 2.96137 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.93577 |
| JADE2 | jade family PHD finger 2 | 2.9116 |
| GPATCH8 | G patch domain containing 8 | 2.8195 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.72265 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | 2.70275 |
| MCM3 | minichromosome maintenance complex component 3 | 2.68885 |
| TNRC6B | trinucleotide repeat containing 6B | 2.67285 |
| KATNIP | katanin interacting protein | 2.6005 |
| MEST | mesoderm specific transcript | 2.56425 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.5605 |
| FOCAD | focadhesin | 2.52765 |
| CCNF | cyclin F | 2.3655 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 2.28058 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.20635 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 2.19035 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | 2.1333 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.12595 |
| SASH1 | SAM and SH3 domain containing 1 | 2.12152 |
| RAB5C | RAB5C, member RAS oncogene family | 2.12005 |
| UROS | uroporphyrinogen III synthase | 2.10255 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 2.04129 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 2.02825 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.01233 |
| ANXA1 | annexin A1 | 2.0057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MRPS2 | mitochondrial ribosomal protein S2 | -5.34405 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.3395 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.1652 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.1479 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.0401 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.9257 |
| PCNA | proliferating cell nuclear antigen | -4.82295 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.55735 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.39818 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.15723 |
| NGRN | neugrin, neurite outgrowth associated | -4.0853 |
| BLCAP | bladder cancer associated protein | -3.8303 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.74645 |
| CCNB2 | cyclin B2 | -3.6035 |
| GNAS | GNAS complex locus | -3.24614 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.11965 |
| TLCD3A | TLC domain containing 3A | -3.0118 |
| GDF15 | growth differentiation factor 15 | -2.89205 |
| GRN | granulin | -2.8489 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.82903 |
| HEATR1 | HEAT repeat containing 1 | -2.66337 |
| PRPF4 | pre-mRNA processing factor 4 | -2.54303 |
| RMI1 | RecQ mediated genome instability 1 | -2.52 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -2.46462 |
| ABITRAM | actin binding transcription modulator | -2.4612 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -2.4507 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 | -2.3848 |
| NREP | neuronal regeneration related protein | -2.35287 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.31255 |
| RNF167 | ring finger protein 167 | -2.19285 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.09635 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) | -2.08415 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -2.08165 |
| PMPCA | peptidase (mitochondrial processing) alpha | -2.06945 |
| SOSTDC1 | sclerostin domain containing 1 | -2.05395 |
| FKTN | fukutin | -2.0393 |
| REV1 | REV1, polymerase (DNA directed) | -2.03625 |
| IFI30 | interferon, gamma-inducible protein 30 | -2.0238 |
