| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tributyl phosphate 4.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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62 genes differentially expressed following the CRCGN011_HEPG2_24H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 5.56345 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.43025 |
| CSK | c-src tyrosine kinase | 5.28395 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.16675 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.149 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.93795 |
| MOK | MOK protein kinase | 4.92065 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.91935 |
| LAGE3 | L antigen family, member 3 | 4.85645 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.81005 |
| CCNF | cyclin F | 4.63605 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.2769 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.5404 |
| ATP11B | ATPase, class VI, type 11B | 3.155 |
| SH3D19 | SH3 domain containing 19 | 3.0084 |
| SNX7 | sorting nexin 7 | 2.666 |
| HMOX1 | heme oxygenase 1 | 2.6495 |
| ICAM1 | intercellular adhesion molecule 1 | 2.62033 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.52325 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.49735 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.4919 |
| NMU | neuromedin U | 2.4908 |
| JADE2 | jade family PHD finger 2 | 2.4563 |
| PRR15L | proline rich 15-like | 2.45315 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.3673 |
| CRLF2 | cytokine receptor-like factor 2 | 2.23235 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2.1048 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.0799 |
| UFM1 | ubiquitin-fold modifier 1 | 2.0579 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 2.055 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | 2.04635 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 2.0398 |
| MYO5C | myosin VC | 2.034 |
| EPHA3 | EPH receptor A3 | 2.02543 |
| TESK2 | testis-specific kinase 2 | 2.00705 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.00075 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MRPS16 | mitochondrial ribosomal protein S16 | -4.8703 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.82335 |
| FAIM | Fas apoptotic inhibitory molecule | -4.76015 |
| DNM1L | dynamin 1-like | -4.607 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.40705 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -4.17815 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.91375 |
| AURKB | aurora kinase B | -3.84495 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.244 |
| CDC25B | cell division cycle 25B | -2.88675 |
| RBM34 | RNA binding motif protein 34 | -2.85612 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -2.4365 |
| SLC28A2 | solute carrier family 28 (concentrative nucleoside transporter), member 2 | -2.3709 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | -2.3467 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.25655 |
| MICU1 | mitochondrial calcium uptake 1 | -2.2016 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.15081 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -2.15055 |
| CDA | cytidine deaminase | -2.1345 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.10504 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.10343 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | -2.0687 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial | -2.0414 |
| UGT1A8 | UDP glucuronosyltransferase 1 family, polypeptide A8 | -2.0247 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.01938 |
| TP53I3 | tumor protein p53 inducible protein 3 | -2.0087 |