CRCGN011_HEPG2_24H:O16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tributyl phosphate 4.95 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

62 genes differentially expressed following the CRCGN011_HEPG2_24H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 5.56345
PPARG peroxisome proliferator-activated receptor gamma 5.43025
CSK c-src tyrosine kinase 5.28395
CARMIL1 capping protein regulator and myosin 1 linker 1 5.16675
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.149
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.93795
MOK MOK protein kinase 4.92065
BACE2 beta-site APP-cleaving enzyme 2 4.91935
LAGE3 L antigen family, member 3 4.85645
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.81005
CCNF cyclin F 4.63605
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.2769
SSBP2 single-stranded DNA binding protein 2 3.5404
ATP11B ATPase, class VI, type 11B 3.155
SH3D19 SH3 domain containing 19 3.0084
SNX7 sorting nexin 7 2.666
HMOX1 heme oxygenase 1 2.6495
ICAM1 intercellular adhesion molecule 1 2.62033
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.52325
ALAS1 5'-aminolevulinate synthase 1 2.49735
GSTZ1 glutathione S-transferase zeta 1 2.4919
NMU neuromedin U 2.4908
JADE2 jade family PHD finger 2 2.4563
PRR15L proline rich 15-like 2.45315
DYNLT3 dynein, light chain, Tctex-type 3 2.3673
CRLF2 cytokine receptor-like factor 2 2.23235
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 2.1048
BIRC2 baculoviral IAP repeat containing 2 2.0799
UFM1 ubiquitin-fold modifier 1 2.0579
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.055
EYA4 EYA transcriptional coactivator and phosphatase 4 2.04635
TGFBI transforming growth factor, beta-induced, 68kDa 2.0398
MYO5C myosin VC 2.034
EPHA3 EPH receptor A3 2.02543
TESK2 testis-specific kinase 2 2.00705
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.00075

decreased expression

Symbol Name Standardized Value
MRPS16 mitochondrial ribosomal protein S16 -4.8703
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.82335
FAIM Fas apoptotic inhibitory molecule -4.76015
DNM1L dynamin 1-like -4.607
KDM3A lysine (K)-specific demethylase 3A -4.40705
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -4.17815
GTPBP8 GTP-binding protein 8 (putative) -3.91375
AURKB aurora kinase B -3.84495
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.244
CDC25B cell division cycle 25B -2.88675
RBM34 RNA binding motif protein 34 -2.85612
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.4365
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -2.3709
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.3467
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.25655
MICU1 mitochondrial calcium uptake 1 -2.2016
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.15081
CXCL11 chemokine (C-X-C motif) ligand 11 -2.15055
CDA cytidine deaminase -2.1345
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.10504
ITGB1BP1 integrin beta 1 binding protein 1 -2.10343
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 -2.0687
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial -2.0414
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 -2.0247
NRIP1 nuclear receptor interacting protein 1 -2.01938
TP53I3 tumor protein p53 inducible protein 3 -2.0087