CRCGN011_HEPG2_24H:O18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tributyl phosphate 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

63 genes differentially expressed following the CRCGN011_HEPG2_24H:O18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 5.682
MYLK myosin light chain kinase 5.4512
RPP38 ribonuclease P/MRP 38kDa subunit 5.2837
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.7047
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.6482
CCL2 chemokine (C-C motif) ligand 2 4.63995
GSTZ1 glutathione S-transferase zeta 1 4.38865
EVL Enah/Vasp-like 3.71295
TIAM1 T-cell lymphoma invasion and metastasis 1 3.46922
SATB1 SATB homeobox 1 3.16925
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.93815
CD40 CD40 molecule, TNF receptor superfamily member 5 2.68566
HMOX1 heme oxygenase 1 2.55925
BAMBI BMP and activin membrane-bound inhibitor 2.4432
TPD52L2 tumor protein D52-like 2 2.3978
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.32612
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.24755
BMP4 bone morphogenetic protein 4 2.22065
CYB561 cytochrome b561 2.17125
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 2.13185
FASTKD5 FAST kinase domains 5 2.1024
COPS7A COP9 signalosome subunit 7A 2.08555
TIMP1 TIMP metallopeptidase inhibitor 1 2.079
SPATA20 spermatogenesis associated 20 2.07315
COQ8A coenzyme Q8A 2.0414
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 2.0052

decreased expression

Symbol Name Standardized Value
KDM3A lysine (K)-specific demethylase 3A -5.6959
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -5.2386
LDHD lactate dehydrogenase D -5.064
C2CD5 C2 calcium-dependent domain containing 5 -4.99065
CCNB2 cyclin B2 -4.8799
PCNA proliferating cell nuclear antigen -4.82295
LAP3 leucine aminopeptidase 3 -4.6975
UGDH UDP-glucose 6-dehydrogenase -4.578
HMG20B high mobility group 20B -3.8977
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.72855
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -3.397
GNAS GNAS complex locus -3.29654
GRWD1 glutamate-rich WD repeat containing 1 -3.19275
ITGB1BP1 integrin beta 1 binding protein 1 -2.8871
ARID5B AT rich interactive domain 5B (MRF1-like) -2.7484
TBC1D31 TBC1 domain family, member 31 -2.5901
IFT81 intraflagellar transport 81 -2.4555
ZW10 zw10 kinetochore protein -2.3633
OXA1L oxidase (cytochrome c) assembly 1-like -2.3573
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.3405
THSD1 thrombospondin, type I, domain containing 1 -2.31125
MED4 mediator complex subunit 4 -2.2762
VAMP4 vesicle-associated membrane protein 4 -2.20327
NBAS neuroblastoma amplified sequence -2.19565
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.18735
EIF5 eukaryotic translation initiation factor 5 -2.16715
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough -2.11805
RASL12 RAS-like, family 12 -2.1134
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -2.11305
IL3RA interleukin 3 receptor, alpha (low affinity) -2.0723
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.0597
BTNL3 butyrophilin-like 3 -2.04635
COMMD10 COMM domain containing 10 -2.03085
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -2.01982
STK38L serine/threonine kinase 38 like -2.0157
IKZF4 IKAROS family zinc finger 4 (Eos) -2.01515
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 -2.00677