| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfafurazole 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN011_HEPG2_24H:O19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.5031 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.43585 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.7419 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.7153 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.4906 |
| CHN1 | chimerin 1 | 4.05645 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.89185 |
| PRKCH | protein kinase C, eta | 3.86658 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 3.66235 |
| BAMBI | BMP and activin membrane-bound inhibitor | 3.6145 |
| JADE2 | jade family PHD finger 2 | 3.45495 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.19355 |
| VGLL4 | vestigial-like family member 4 | 2.87147 |
| CHEK2 | checkpoint kinase 2 | 2.62745 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | 2.58763 |
| KIFBP | kinesin family binding protein | 2.5671 |
| PLSCR3 | phospholipid scramblase 3 | 2.38307 |
| FASTKD5 | FAST kinase domains 5 | 2.3688 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.36305 |
| CSNK1A1 | casein kinase 1, alpha 1 | 2.27513 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.2373 |
| MEST | mesoderm specific transcript | 2.21045 |
| COL11A1 | collagen, type XI, alpha 1 | 2.2025 |
| TPD52L2 | tumor protein D52-like 2 | 2.16135 |
| GPATCH8 | G patch domain containing 8 | 2.11893 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.0821 |
| DCLRE1B | DNA cross-link repair 1B | 2.0674 |
| PTBP1 | polypyrimidine tract binding protein 1 | 2.06735 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.0671 |
| HOMER1 | homer scaffolding protein 1 | 2.0587 |
| EGR3 | early growth response 3 | 2.043 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.1243 |
| TRIB3 | tribbles pseudokinase 3 | -5.22595 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -5.0954 |
| DNM1L | dynamin 1-like | -4.9777 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.82905 |
| NUP85 | nucleoporin 85kDa | -4.80435 |
| LDHD | lactate dehydrogenase D | -4.74165 |
| CHMP4B | charged multivesicular body protein 4B | -4.59348 |
| MAP7 | microtubule-associated protein 7 | -4.57537 |
| CCDC86 | coiled-coil domain containing 86 | -4.3586 |
| ADI1 | acireductone dioxygenase 1 | -3.7235 |
| GNAS | GNAS complex locus | -3.6137 |
| PCNA | proliferating cell nuclear antigen | -3.5869 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.52115 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.0431 |
| MRPS7 | mitochondrial ribosomal protein S7 | -3.01555 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.956 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.84465 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.7898 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.77108 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.76727 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -2.442 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.41115 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.3925 |
| CPNE3 | copine III | -2.38785 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.34728 |
| TRIP4 | thyroid hormone receptor interactor 4 | -2.3311 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -2.3108 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.28545 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | -2.2559 |
| GRB2 | growth factor receptor-bound protein 2 | -2.1636 |
| LRRC59 | leucine rich repeat containing 59 | -2.1413 |
| ELMO2 | engulfment and cell motility 2 | -2.11968 |
| CIDEB | cell death-inducing DFFA-like effector b | -2.10535 |
| TEX14 | testis expressed 14 | -2.0878 |
| SAP30BP | SAP30 binding protein | -2.0311 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -2.02973 |
| TCTA | T-cell leukemia translocation altered | -2.02045 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.00825 |
