| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfafurazole 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN011_HEPG2_24H:O20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.23955 |
| RPL39L | ribosomal protein L39-like | 5.23655 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.15355 |
| MYLK | myosin light chain kinase | 5.0407 |
| CSK | c-src tyrosine kinase | 4.91515 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.4652 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.32305 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.11469 |
| MAP7 | microtubule-associated protein 7 | 4.07212 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.80492 |
| PRKCH | protein kinase C, eta | 3.77537 |
| CYCS | cytochrome c, somatic | 3.62505 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.30307 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.24135 |
| KLHL9 | kelch-like family member 9 | 2.96165 |
| CCNF | cyclin F | 2.73115 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.66335 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.65745 |
| CTPS1 | CTP synthase 1 | 2.4838 |
| PMM2 | phosphomannomutase 2 | 2.4528 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.315 |
| IFI44L | interferon-induced protein 44-like | 2.27195 |
| PRDX1 | peroxiredoxin 1 | 2.25595 |
| GPATCH8 | G patch domain containing 8 | 2.1982 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | 2.1786 |
| JADE2 | jade family PHD finger 2 | 2.10243 |
| DIPK1A | divergent protein kinase domain 1A | 2.0673 |
| H2BC12 | H2B clustered histone 12 | 2.04833 |
| PER3 | period circadian clock 3 | 2.0247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.83365 |
| CD320 | CD320 molecule | -5.33725 |
| CDC20 | cell division cycle 20 | -5.0 |
| LDHD | lactate dehydrogenase D | -4.9891 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.886 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.76065 |
| THAP11 | THAP domain containing 11 | -4.63855 |
| TLCD3A | TLC domain containing 3A | -4.33 |
| GDF15 | growth differentiation factor 15 | -4.2744 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.76815 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.03858 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.01075 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.00934 |
| WDR7 | WD repeat domain 7 | -2.98285 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.75147 |
| RPS5 | ribosomal protein S5 | -2.51365 |
| GPA33 | glycoprotein A33 (transmembrane) | -2.48 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.29642 |
| TCF12 | transcription factor 12 | -2.27505 |
| KLHL25 | kelch-like family member 25 | -2.27045 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.26542 |
| PAX1 | paired box 1 | -2.1813 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 | -2.16945 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -2.15955 |
| MEGF6 | multiple EGF-like-domains 6 | -2.15695 |
| BORCS8 | BLOC-1 related complex subunit 8 | -2.14175 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.13003 |
| RGS2 | regulator of G-protein signaling 2 | -2.12155 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.11147 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | -2.09305 |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 | -2.0848 |
| TRIP4 | thyroid hormone receptor interactor 4 | -2.0793 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | -2.06185 |
| CHP2 | calcineurin-like EF-hand protein 2 | -2.0103 |
