| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfafurazole 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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67 genes differentially expressed following the CRCGN011_HEPG2_24H:O21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 5.7212 |
| STK10 | serine/threonine kinase 10 | 5.6531 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.3203 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.0309 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.70215 |
| CBR3 | carbonyl reductase 3 | 3.923 |
| GATA3 | GATA binding protein 3 | 3.88467 |
| TLR4 | toll-like receptor 4 | 3.71035 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 3.686 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.29072 |
| PRR15L | proline rich 15-like | 3.10805 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.94318 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.6915 |
| JADE2 | jade family PHD finger 2 | 2.5002 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.40355 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.38285 |
| DENR | density-regulated protein | 2.22555 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial | 2.1732 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 2.16735 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.11335 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.10355 |
| CCNE2 | cyclin E2 | 2.09835 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.0915 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G | 2.0715 |
| SERF1A | small EDRK-rich factor 1A (telomeric) | 2.06435 |
| SLC25A46 | solute carrier family 25, member 46 | 2.0511 |
| HACL2 | 2-hydroxyacyl-CoA lyase 2 | 2.04703 |
| TWNK | twinkle mtDNA helicase | 2.02745 |
| CCNF | cyclin F | 2.01105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.1706 |
| ZNF586 | zinc finger protein 586 | -6.69985 |
| TUBB6 | tubulin, beta 6 class V | -5.0907 |
| CDC20 | cell division cycle 20 | -4.66275 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.2852 |
| GNAS | GNAS complex locus | -3.78501 |
| ADI1 | acireductone dioxygenase 1 | -3.63575 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -3.07032 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.9455 |
| ZNF134 | zinc finger protein 134 | -2.9029 |
| SLC35F2 | solute carrier family 35, member F2 | -2.77 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.6087 |
| ZNF211 | zinc finger protein 211 | -2.5442 |
| PRPF4 | pre-mRNA processing factor 4 | -2.53975 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -2.4232 |
| ZNF419 | zinc finger protein 419 | -2.37035 |
| IPO13 | importin 13 | -2.3369 |
| PDZD2 | PDZ domain containing 2 | -2.30495 |
| ZNF551 | zinc finger protein 551 | -2.2799 |
| PRODH2 | proline dehydrogenase (oxidase) 2 | -2.2487 |
| TOM1L2 | target of myb1-like 2 (chicken) | -2.24205 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.2323 |
| FZD8 | frizzled class receptor 8 | -2.2086 |
| ZNF93 | zinc finger protein 93 | -2.19653 |
| IL36R | interleukin 36 receptor | -2.17395 |
| ZKSCAN7 | zinc finger with KRAB and SCAN domains 7 | -2.17295 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.1565 |
| ZNF548 | zinc finger protein 548 | -2.1316 |
| EDN2 | endothelin 2 | -2.11605 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 | -2.08545 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.08297 |
| ZNF532 | zinc finger protein 532 | -2.07065 |
| CD1C | CD1c molecule | -2.06765 |
| ZNF304 | zinc finger protein 304 | -2.0504 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.04885 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.04798 |
| ROGDI | rogdi homolog (Drosophila) | -2.03645 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 | -2.0313 |