| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfafurazole 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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94 genes differentially expressed following the CRCGN011_HEPG2_24H:O22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 10.0 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 6.07775 |
| MCOLN1 | mucolipin 1 | 5.3678 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.16845 |
| E2F2 | E2F transcription factor 2 | 5.02295 |
| KLHL21 | kelch-like family member 21 | 4.98515 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.9428 |
| STK10 | serine/threonine kinase 10 | 4.8099 |
| ATP11B | ATPase, class VI, type 11B | 4.8074 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.7419 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.4339 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.4332 |
| NOSIP | nitric oxide synthase interacting protein | 4.3946 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.3536 |
| EVL | Enah/Vasp-like | 3.8549 |
| GPATCH8 | G patch domain containing 8 | 3.48165 |
| TLR4 | toll-like receptor 4 | 3.39055 |
| RNF144A | ring finger protein 144A | 3.15975 |
| COL11A1 | collagen, type XI, alpha 1 | 2.89478 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.8858 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.67721 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.64928 |
| CLASRP | CLK4-associating serine/arginine rich protein | 2.55945 |
| XYLT1 | xylosyltransferase I | 2.55005 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.47285 |
| DIPK1A | divergent protein kinase domain 1A | 2.34885 |
| TRIM52 | tripartite motif containing 52 | 2.3462 |
| FBXO46 | F-box protein 46 | 2.345 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.32528 |
| HOXC10 | homeobox C10 | 2.29815 |
| RPAP1 | RNA polymerase II associated protein 1 | 2.29495 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2.2039 |
| B4GALT3 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 | 2.18815 |
| CARM1 | coactivator-associated arginine methyltransferase 1 | 2.185 |
| MEST | mesoderm specific transcript | 2.1781 |
| IFI6 | interferon, alpha-inducible protein 6 | 2.17725 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 2.14675 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 2.13705 |
| CYCS | cytochrome c, somatic | 2.13215 |
| LAMB3 | laminin, beta 3 | 2.1298 |
| APOD | apolipoprotein D | 2.1262 |
| COQ8A | coenzyme Q8A | 2.1082 |
| MARCHF8 | membrane associated ring-CH-type finger 8 | 2.0944 |
| MAP7D1 | MAP7 domain containing 1 | 2.09205 |
| NOL9 | nucleolar protein 9 | 2.08595 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 2.0854 |
| PORCN | porcupine homolog (Drosophila) | 2.0531 |
| CHSY1 | chondroitin sulfate synthase 1 | 2.0346 |
| LIF | leukemia inhibitory factor | 2.01705 |
| LOC124907090 | ankyrin repeat domain-containing protein SOWAHC-like | 2.0138 |
| SIPA1 | signal-induced proliferation-associated 1 | 2.0029 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.40855 |
| LDHD | lactate dehydrogenase D | -5.0484 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.8973 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.89525 |
| MAP7 | microtubule-associated protein 7 | -4.81802 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.56235 |
| CD320 | CD320 molecule | -4.41805 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.29545 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -4.2592 |
| PCNA | proliferating cell nuclear antigen | -4.2072 |
| WASHC4 | WASH complex subunit 4 | -3.7347 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.71537 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.47367 |
| BDNF | brain-derived neurotrophic factor | -2.98885 |
| TBCB | tubulin folding cofactor B | -2.76187 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.58092 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.57185 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.5121 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.5113 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -2.43235 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -2.36365 |
| ZNF146 | zinc finger protein 146 | -2.35795 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.35195 |
| GDF15 | growth differentiation factor 15 | -2.2152 |
| PODXL | podocalyxin-like | -2.21245 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | -2.18295 |
| UNC13B | unc-13 homolog B (C. elegans) | -2.1193 |
| GALNT15 | polypeptide N-acetylgalactosaminyltransferase 15 | -2.1051 |
| WDR25 | WD repeat domain 25 | -2.0868 |
| CCNH | cyclin H | -2.07825 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.06624 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.0555 |
| FAM32A | family with sequence similarity 32, member A | -2.04735 |
| PLPP3 | phospholipid phosphatase 3 | -2.03538 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | -2.02965 |
| TCN2 | transcobalamin II | -2.029 |
| USF2 | upstream transcription factor 2, c-fos interacting | -2.02747 |
| TMEM147 | transmembrane protein 147 | -2.02075 |
| RASL12 | RAS-like, family 12 | -2.0178 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | -2.01775 |
| SDHAF1 | succinate dehydrogenase complex assembly factor 1 | -2.01763 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -2.01087 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 | -2.00505 |
