| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dehydroepiandrosterone 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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101 genes differentially expressed following the CRCGN011_HEPG2_24H:P04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 5.2287 |
| CHMP6 | charged multivesicular body protein 6 | 5.0638 |
| NMU | neuromedin U | 5.0192 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.0022 |
| UBQLN2 | ubiquilin 2 | 4.95955 |
| CSK | c-src tyrosine kinase | 4.66275 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.62895 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.16565 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.92915 |
| ABHD4 | abhydrolase domain containing 4 | 3.8108 |
| PRKCH | protein kinase C, eta | 3.59707 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.4621 |
| BAD | BCL2-associated agonist of cell death | 3.2921 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.2822 |
| MEST | mesoderm specific transcript | 2.64705 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 2.53165 |
| NNT | nicotinamide nucleotide transhydrogenase | 2.50312 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 2.43875 |
| MELK | maternal embryonic leucine zipper kinase | 2.40095 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 2.36628 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 2.36085 |
| DENR | density-regulated protein | 2.33505 |
| HMG20B | high mobility group 20B | 2.3064 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | 2.29905 |
| SYCP2 | synaptonemal complex protein 2 | 2.2964 |
| NUP153 | nucleoporin 153kDa | 2.29575 |
| VGLL4 | vestigial-like family member 4 | 2.28157 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 2.2568 |
| TAC1 | tachykinin, precursor 1 | 2.2405 |
| CD320 | CD320 molecule | 2.2386 |
| DNM1L | dynamin 1-like | 2.2166 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I | 2.20285 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.2008 |
| NLRP2B | NLR family pyrin domain containing 2B | 2.18425 |
| HELZ | helicase with zinc finger | 2.1641 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 2.13255 |
| NDRG3 | NDRG family member 3 | 2.1268 |
| PGAM4 | phosphoglycerate mutase family member 4 | 2.1207 |
| MRPL12 | mitochondrial ribosomal protein L12 | 2.1004 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.09735 |
| FASTKD5 | FAST kinase domains 5 | 2.09175 |
| JMJD1C | jumonji domain containing 1C | 2.0879 |
| MCOLN1 | mucolipin 1 | 2.0735 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 2.06325 |
| PDLIM1 | PDZ and LIM domain 1 | 2.01985 |
| CYBC1 | cytochrome b-245 chaperone 1 | 2.00425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLCD3A | TLC domain containing 3A | -6.74775 |
| CDC20 | cell division cycle 20 | -5.31545 |
| ZNF586 | zinc finger protein 586 | -4.9264 |
| LAP3 | leucine aminopeptidase 3 | -4.7241 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.36635 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.35975 |
| PCNA | proliferating cell nuclear antigen | -4.2322 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.1075 |
| BMP4 | bone morphogenetic protein 4 | -3.4925 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.3702 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.3582 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.13555 |
| CCNB2 | cyclin B2 | -3.002 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.97415 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.8786 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.83515 |
| NHEJ1 | nonhomologous end-joining factor 1 | -2.7055 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -2.5595 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.54525 |
| FAM222B | family with sequence similarity 222, member B | -2.49515 |
| MED27 | mediator complex subunit 27 | -2.4808 |
| CDC25B | cell division cycle 25B | -2.46965 |
| SQOR | sulfide quinone oxidoreductase | -2.4483 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.44712 |
| DDN | dendrin | -2.43045 |
| FAIM | Fas apoptotic inhibitory molecule | -2.35345 |
| KRT6B | keratin 6B, type II | -2.29675 |
| KIF2C | kinesin family member 2C | -2.26235 |
| CD38 | CD38 molecule | -2.24215 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -2.23565 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide | -2.2235 |
| VPS52 | vacuolar protein sorting 52 homolog (S. cerevisiae) | -2.17725 |
| SDC1 | syndecan 1 | -2.1696 |
| GPN2 | GPN-loop GTPase 2 | -2.1635 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.15295 |
| MUC13 | mucin 13, cell surface associated | -2.13525 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 | -2.12365 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa | -2.12135 |
| PRRX2 | paired related homeobox 2 | -2.1087 |
| HSPA1A | heat shock 70kDa protein 1A | -2.1018 |
| TSC1 | tuberous sclerosis 1 | -2.0975 |
| BTNL8 | butyrophilin-like 8 | -2.091 |
| FEV | FEV (ETS oncogene family) | -2.0809 |
| SLC35F2 | solute carrier family 35, member F2 | -2.07185 |
| IL7R | interleukin 7 receptor | -2.0686 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -2.06265 |
| IPO13 | importin 13 | -2.05295 |
| ANAPC2 | anaphase promoting complex subunit 2 | -2.04665 |
| ZNF747 | zinc finger protein 747 | -2.04465 |
| PRPF4 | pre-mRNA processing factor 4 | -2.04418 |
| SPOUT1 | SPOUT domain containing methyltransferase 1 | -2.0366 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -2.03347 |
| CRMP1 | collapsin response mediator protein 1 | -2.03345 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.0257 |
| TFCP2L1 | transcription factor CP2-like 1 | -2.00495 |
