| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dehydroepiandrosterone 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
74 genes differentially expressed following the CRCGN011_HEPG2_24H:P06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.90445 |
| STIMATE | STIM activating enhancer | 5.27675 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 5.192 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 4.98445 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.59855 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.449 |
| MSRA | methionine sulfoxide reductase A | 4.39075 |
| PRKCQ | protein kinase C, theta | 4.25292 |
| ABHD6 | abhydrolase domain containing 6 | 4.22663 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.22335 |
| EAPP | E2F-associated phosphoprotein | 4.17375 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.86433 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.86267 |
| SIRT3 | sirtuin 3 | 3.55697 |
| NMU | neuromedin U | 3.03245 |
| CHEK2 | checkpoint kinase 2 | 2.88028 |
| MEST | mesoderm specific transcript | 2.61105 |
| BLMH | bleomycin hydrolase | 2.5708 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.52128 |
| CCNF | cyclin F | 2.51267 |
| PRR15L | proline rich 15-like | 2.4861 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | 2.47933 |
| VGLL4 | vestigial-like family member 4 | 2.4498 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 | 2.4102 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 2.2664 |
| PLSCR3 | phospholipid scramblase 3 | 2.2231 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 2.209 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.17525 |
| DEAF1 | DEAF1 transcription factor | 2.16565 |
| RLBP1 | retinaldehyde binding protein 1 | 2.13765 |
| SS18L2 | synovial sarcoma translocation gene on chromosome 18-like 2 | 2.11175 |
| RNF170 | ring finger protein 170 | 2.0564 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 2.0328 |
| CYCS | cytochrome c, somatic | 2.02305 |
| CHN1 | chimerin 1 | 2.0061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.605 |
| RPIA | ribose 5-phosphate isomerase A | -5.1617 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.0 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -4.8094 |
| LDHD | lactate dehydrogenase D | -4.74165 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.4568 |
| EIF5 | eukaryotic translation initiation factor 5 | -4.06032 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.881 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.60685 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.2288 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -3.1789 |
| MTA1 | metastasis associated 1 | -2.83165 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.72228 |
| CMTR1 | cap methyltransferase 1 | -2.714 |
| MVP | major vault protein | -2.66415 |
| ATAD2B | ATPase family, AAA domain containing 2B | -2.6302 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.45568 |
| TMEM230 | transmembrane protein 230 | -2.44745 |
| SNX5 | sorting nexin 5 | -2.3916 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | -2.34715 |
| VTN | vitronectin | -2.32465 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.317 |
| WASHC4 | WASH complex subunit 4 | -2.29192 |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide | -2.21895 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.19725 |
| PEF1 | penta-EF-hand domain containing 1 | -2.19055 |
| STBD1 | starch binding domain 1 | -2.18535 |
| PANK2 | pantothenate kinase 2 | -2.17345 |
| SLC19A3 | solute carrier family 19 (thiamine transporter), member 3 | -2.17245 |
| C5 | complement component 5 | -2.1377 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.0987 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -2.07395 |
| PLIN1 | perilipin 1 | -2.04185 |
| ADA | adenosine deaminase | -2.04095 |
| FNDC3B | fibronectin type III domain containing 3B | -2.02235 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -2.00905 |
| TMEM208 | transmembrane protein 208 | -2.0072 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.0055 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -2.00225 |
