CRCGN011_HEPG2_24H:P15 Gene Set
Genes
45 genes differentially expressed following the CRCGN011_HEPG2_24H:P15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.398
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
5.35145
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.69355
|
|
STK10
|
serine/threonine kinase 10
|
3.817
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
3.44025
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.26975
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
3.2394
|
|
CHN1
|
chimerin 1
|
3.1107
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.04177
|
|
VGLL4
|
vestigial-like family member 4
|
3.01662
|
|
KLHL9
|
kelch-like family member 9
|
2.77487
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.77097
|
|
JADE2
|
jade family PHD finger 2
|
2.71995
|
|
HMOX1
|
heme oxygenase 1
|
2.52175
|
|
LCN2
|
lipocalin 2
|
2.413
|
|
PLOD3
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
|
2.33305
|
|
CHEK2
|
checkpoint kinase 2
|
2.30948
|
|
CEP57
|
centrosomal protein 57kDa
|
2.27588
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
2.25515
|
|
ALG9
|
ALG9, alpha-1,2-mannosyltransferase
|
2.19715
|
|
FOCAD
|
focadhesin
|
2.06675
|
|
CYCS
|
cytochrome c, somatic
|
2.0509
|
|
PTCD3
|
pentatricopeptide repeat domain 3
|
2.0409
|
|
SATB1
|
SATB homeobox 1
|
2.02815
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-5.06615
|
|
DUSP6
|
dual specificity phosphatase 6
|
-4.65353
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.6109
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.3586
|
|
CDC20
|
cell division cycle 20
|
-4.2518
|
|
CCNB2
|
cyclin B2
|
-4.24455
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.18535
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.5488
|
|
FBXO7
|
F-box protein 7
|
-2.9105
|
|
ETNK1
|
ethanolamine kinase 1
|
-2.8288
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.77055
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.48245
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.37145
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.1578
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.13845
|
|
CDK7
|
cyclin-dependent kinase 7
|
-2.13275
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.08945
|
|
RASGRP1
|
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
|
-2.0705
|
|
FCER1A
|
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
|
-2.0514
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.0444
|
|
ARL4A
|
ADP-ribosylation factor-like 4A
|
-2.03065
|
