| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-(4-aminobenzyl)phenylamine 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN011_HEPG2_24H:P17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCOLN1 | mucolipin 1 | 6.463 |
| CHMP6 | charged multivesicular body protein 6 | 5.38835 |
| STIMATE | STIM activating enhancer | 5.22145 |
| NOTCH1 | notch 1 | 5.09855 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.02965 |
| ABHD6 | abhydrolase domain containing 6 | 3.78667 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.57678 |
| CYCS | cytochrome c, somatic | 3.5647 |
| MEST | mesoderm specific transcript | 3.21355 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.95365 |
| STAT5B | signal transducer and activator of transcription 5B | 2.87597 |
| HYAL2 | hyaluronoglucosaminidase 2 | 2.8192 |
| BCORL1 | BCL6 corepressor-like 1 | 2.8121 |
| HDAC7 | histone deacetylase 7 | 2.71055 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.68603 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 2.5495 |
| TRAFD1 | TRAF-type zinc finger domain containing 1 | 2.46257 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.40215 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.38762 |
| INSIG1 | insulin induced gene 1 | 2.35452 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.28695 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | 2.20715 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.19725 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 2.17065 |
| CES3 | carboxylesterase 3 | 2.1539 |
| CLSTN3 | calsyntenin 3 | 2.1121 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 2.10505 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | 2.09645 |
| CHN1 | chimerin 1 | 2.0911 |
| NOSIP | nitric oxide synthase interacting protein | 2.0803 |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) | 2.05925 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 2.0528 |
| CLCN7 | chloride channel, voltage-sensitive 7 | 2.01185 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| CDC20 | cell division cycle 20 | -10.0 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.2656 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -5.1921 |
| ADI1 | acireductone dioxygenase 1 | -5.10555 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.6938 |
| TRIB3 | tribbles pseudokinase 3 | -4.384 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.93555 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.66135 |
| CCNB2 | cyclin B2 | -3.61355 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -3.55908 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.30465 |
| VDAC1 | voltage-dependent anion channel 1 | -3.26757 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.21887 |
| PCNA | proliferating cell nuclear antigen | -3.02885 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.82155 |
| HEATR1 | HEAT repeat containing 1 | -2.81682 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -2.77265 |
| VPREB1 | pre-B lymphocyte 1 | -2.61285 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.59345 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -2.4949 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -2.4685 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.4609 |
| CDC25B | cell division cycle 25B | -2.45035 |
| CCDC81 | coiled-coil domain containing 81 | -2.44785 |
| EXO5 | exonuclease 5 | -2.3347 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 | -2.30845 |
| POPDC3 | popeye domain containing 3 | -2.2299 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.2279 |
| SCIN | scinderin | -2.2197 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -2.17815 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.15695 |
| CRNN | cornulin | -2.15515 |
| PCDHB16 | protocadherin beta 16 | -2.12625 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -2.0932 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | -2.06325 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -2.05922 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -2.0057 |
