CRCGN011_HEPG2_24H:P18 Gene Set
Genes
51 genes differentially expressed following the CRCGN011_HEPG2_24H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.3084
|
|
UBQLN2
|
ubiquilin 2
|
5.19575
|
|
E2F2
|
E2F transcription factor 2
|
5.16985
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.13835
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.96415
|
|
NOTCH1
|
notch 1
|
4.686
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.9007
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.804
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.744
|
|
PRR15L
|
proline rich 15-like
|
3.67875
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.6538
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.61295
|
|
JADE2
|
jade family PHD finger 2
|
3.17545
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.09358
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.89955
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.7828
|
|
CYCS
|
cytochrome c, somatic
|
2.6487
|
|
PKN1
|
protein kinase N1
|
2.53067
|
|
CCL22
|
chemokine (C-C motif) ligand 22
|
2.39735
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
2.335
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.32064
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.31502
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.204
|
|
BAHD1
|
bromo adjacent homology domain containing 1
|
2.16555
|
|
SLC9A2
|
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
|
2.13165
|
|
ASL
|
argininosuccinate lyase
|
2.1002
|
|
CDK10
|
cyclin-dependent kinase 10
|
2.0477
|
|
PURA
|
purine-rich element binding protein A
|
2.02397
|
|
ACP2
|
acid phosphatase 2, lysosomal
|
2.0196
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-8.70745
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.9241
|
|
VAT1
|
vesicle amine transport 1
|
-4.91095
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.82295
|
|
LDHD
|
lactate dehydrogenase D
|
-4.7459
|
|
DNM1L
|
dynamin 1-like
|
-4.6197
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.5666
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.34165
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.7471
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.5701
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.40303
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.92368
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.69858
|
|
LORICRIN
|
loricrin cornified envelope precursor protein
|
-2.5177
|
|
CCNO
|
cyclin O
|
-2.42005
|
|
GDF15
|
growth differentiation factor 15
|
-2.368
|
|
TUBB6
|
tubulin, beta 6 class V
|
-2.2202
|
|
CHEK1
|
checkpoint kinase 1
|
-2.13357
|
|
CGGBP1
|
CGG triplet repeat binding protein 1
|
-2.0497
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.0184
|
|
FKBP9
|
FK506 binding protein 9, 63 kDa
|
-2.01
|
|
CAVIN1
|
caveolae associated protein 1
|
-2.00717
|
