CRCGN011_HEPG2_24H:P21 Gene Set
Genes
51 genes differentially expressed following the CRCGN011_HEPG2_24H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
10.0
|
|
STIMATE
|
STIM activating enhancer
|
9.7542
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.8385
|
|
STAP2
|
signal transducing adaptor family member 2
|
5.3562
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.8857
|
|
LCN2
|
lipocalin 2
|
4.60205
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.5804
|
|
TLR4
|
toll-like receptor 4
|
4.4497
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.08015
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
4.02647
|
|
HOXA10
|
homeobox A10
|
4.00665
|
|
STK10
|
serine/threonine kinase 10
|
3.81853
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
3.74825
|
|
EPN2
|
epsin 2
|
3.62655
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
3.5904
|
|
MAP7
|
microtubule-associated protein 7
|
3.4518
|
|
CYCS
|
cytochrome c, somatic
|
3.27095
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.06345
|
|
GATA3
|
GATA binding protein 3
|
3.04607
|
|
SGCB
|
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
|
2.5466
|
|
EXOSC4
|
exosome component 4
|
2.47975
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.43547
|
|
VGLL4
|
vestigial-like family member 4
|
2.31568
|
|
NOTCH2NLB
|
notch 2 N-terminal like B
|
2.2536
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.1909
|
|
GINS2
|
GINS complex subunit 2 (Psf2 homolog)
|
2.15625
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.1294
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.08745
|
|
ARPP19
|
cAMP-regulated phosphoprotein, 19kDa
|
2.05032
|
|
PRR11
|
proline rich 11
|
2.00005
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.95875
|
|
LDHD
|
lactate dehydrogenase D
|
-4.85865
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.69045
|
|
GNAS
|
GNAS complex locus
|
-3.67999
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.4669
|
|
RAI14
|
retinoic acid induced 14
|
-3.3984
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.3431
|
|
CCNB2
|
cyclin B2
|
-3.10825
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.0092
|
|
WASHC4
|
WASH complex subunit 4
|
-2.91057
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.7682
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.6669
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.64902
|
|
PPP2R5A
|
protein phosphatase 2, regulatory subunit B', alpha
|
-2.62797
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.51713
|
|
ZNF274
|
zinc finger protein 274
|
-2.38815
|
|
NVL
|
nuclear VCP-like
|
-2.35425
|
|
RNF167
|
ring finger protein 167
|
-2.17015
|
|
TMPRSS11D
|
transmembrane protease, serine 11D
|
-2.10785
|
|
NUCKS1
|
nuclear casein kinase and cyclin-dependent kinase substrate 1
|
-2.05445
|
|
ACTR6
|
ARP6 actin-related protein 6 homolog (yeast)
|
-2.02625
|
