CRCGN011_HEPG2_24H:P22 Gene Set
Genes
37 genes differentially expressed following the CRCGN011_HEPG2_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
7.7253
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
6.40487
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.55315
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.20265
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.8556
|
|
STK10
|
serine/threonine kinase 10
|
4.68217
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.65382
|
|
STIMATE
|
STIM activating enhancer
|
4.3545
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.56535
|
|
PRKCH
|
protein kinase C, eta
|
3.3804
|
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1
|
2.40645
|
|
COQ8A
|
coenzyme Q8A
|
2.34795
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.3328
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.32685
|
|
DDX49
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
|
2.199
|
|
ENY2
|
enhancer of yellow 2 homolog (Drosophila)
|
2.16075
|
|
POLR2K
|
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
|
2.16053
|
|
IGLL1
|
immunoglobulin lambda-like polypeptide 1
|
2.09605
|
|
LAMA2
|
laminin, alpha 2
|
2.0495
|
|
HTD2
|
hydroxyacyl-thioester dehydratase type 2
|
2.0404
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.04015
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.06735
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.79885
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.4817
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.17513
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.14125
|
|
HMG20B
|
high mobility group 20B
|
-4.0828
|
|
GNAS
|
GNAS complex locus
|
-3.17917
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-2.9677
|
|
S100A10
|
S100 calcium binding protein A10
|
-2.3826
|
|
DPPA4
|
developmental pluripotency associated 4
|
-2.2578
|
|
GNG11
|
guanine nucleotide binding protein (G protein), gamma 11
|
-2.1801
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.133
|
|
ITK
|
IL2-inducible T-cell kinase
|
-2.0558
|
|
HAS2
|
hyaluronan synthase 2
|
-2.04895
|
|
GPR171
|
G protein-coupled receptor 171
|
-2.02945
|
