| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzoin 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
108 genes differentially expressed following the CRCGN011_HEPG2_24H:P24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 10.0 |
| CYCS | cytochrome c, somatic | 5.92495 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 5.77005 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.28665 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 5.16365 |
| MCOLN1 | mucolipin 1 | 5.1569 |
| MOK | MOK protein kinase | 4.35105 |
| EVL | Enah/Vasp-like | 4.32715 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.02365 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.94115 |
| COQ8A | coenzyme Q8A | 3.71145 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 3.51512 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.23335 |
| PFKL | phosphofructokinase, liver | 3.22148 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 3.16735 |
| JADE2 | jade family PHD finger 2 | 3.134 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.9368 |
| CLBA1 | clathrin binding box of aftiphilin containing 1 | 2.64425 |
| PHOX2A | paired-like homeobox 2a | 2.46345 |
| HSPA1A | heat shock 70kDa protein 1A | 2.4389 |
| GPATCH8 | G patch domain containing 8 | 2.41108 |
| TAGLN2 | transgelin 2 | 2.32105 |
| TRIM9 | tripartite motif containing 9 | 2.30105 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.26005 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | 2.24025 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.2041 |
| NUP42 | nucleoporin 42 | 2.1972 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 2.19125 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 2.1896 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.18475 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 2.1846 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | 2.1766 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 | 2.15045 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | 2.147 |
| CISD1 | CDGSH iron sulfur domain 1 | 2.14195 |
| YY1AP1 | YY1 associated protein 1 | 2.1419 |
| GRAMD4 | GRAM domain containing 4 | 2.1354 |
| FXYD7 | FXYD domain containing ion transport regulator 7 | 2.1133 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 2.08625 |
| TRAPPC10 | trafficking protein particle complex 10 | 2.07428 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.06745 |
| MRM2 | mitochondrial rRNA methyltransferase 2 | 2.05883 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 2.057 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 2.05515 |
| GPR162 | G protein-coupled receptor 162 | 2.0446 |
| VPS9D1 | VPS9 domain containing 1 | 2.042 |
| MAOB | monoamine oxidase B | 2.04005 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 2.03985 |
| GFER | growth factor, augmenter of liver regeneration | 2.03575 |
| NCAN | neurocan | 2.0336 |
| SPAG4 | sperm associated antigen 4 | 2.01645 |
| LTK | leukocyte receptor tyrosine kinase | 2.01428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC20 | cell division cycle 20 | -10.0 |
| CCNB2 | cyclin B2 | -7.8421 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.4038 |
| SCAND1 | SCAN domain containing 1 | -5.2181 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.90965 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.74795 |
| LDHD | lactate dehydrogenase D | -4.691 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.3866 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.06625 |
| THAP11 | THAP domain containing 11 | -3.8093 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.58435 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.44702 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.39795 |
| IFRD2 | interferon-related developmental regulator 2 | -3.30285 |
| GNAS | GNAS complex locus | -3.12854 |
| TRAP1 | TNF receptor-associated protein 1 | -2.8793 |
| WDR5B | WD repeat domain 5B | -2.7625 |
| GIMAP4 | GTPase, IMAP family member 4 | -2.71365 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.70627 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -2.63705 |
| TMEM35B | transmembrane protein 35B | -2.60562 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -2.49445 |
| ZNF175 | zinc finger protein 175 | -2.4598 |
| IER2 | immediate early response 2 | -2.4066 |
| SCN2A | sodium channel, voltage gated, type II alpha subunit | -2.3771 |
| ANKRD55 | ankyrin repeat domain 55 | -2.3564 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.33805 |
| IGSF6 | immunoglobulin superfamily, member 6 | -2.3321 |
| RASA2 | RAS p21 protein activator 2 | -2.3145 |
| SLC35A5 | solute carrier family 35, member A5 | -2.28365 |
| GTPBP2 | GTP binding protein 2 | -2.2826 |
| DCXR | dicarbonyl/L-xylulose reductase | -2.26375 |
| TMEM223 | transmembrane protein 223 | -2.2608 |
| CHMP5 | charged multivesicular body protein 5 | -2.23255 |
| PEDS1 | plasmanylethanolamine desaturase 1 | -2.2265 |
| SQOR | sulfide quinone oxidoreductase | -2.1735 |
| FOXL1 | forkhead box L1 | -2.1603 |
| FHIT | fragile histidine triad | -2.14595 |
| SH3GL2 | SH3-domain GRB2-like 2 | -2.14385 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -2.1391 |
| CRBN | cereblon | -2.13055 |
| MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) | -2.1171 |
| UFSP2 | UFM1-specific peptidase 2 | -2.0914 |
| STOML2 | stomatin (EPB72)-like 2 | -2.0854 |
| HOXB2 | homeobox B2 | -2.08235 |
| BCHE | butyrylcholinesterase | -2.07945 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | -2.06825 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.0638 |
| LOC102724652 | alpha-crystallin A chain | -2.0459 |
| GPR18 | G protein-coupled receptor 18 | -2.02995 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -2.01855 |
| CREB3L4 | cAMP responsive element binding protein 3-like 4 | -2.0166 |
| POGLUT2 | protein O-glucosyltransferase 2 | -2.01495 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein | -2.00675 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) | -2.00505 |
| ICE2 | interactor of little elongation complex ELL subunit 2 | -2.0003 |
