| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN012_HEPG2_24H:A03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.92853 |
| LCN2 | lipocalin 2 | 4.94611 |
| MOK | MOK protein kinase | 4.93135 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.54802 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.27104 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 3.84408 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.56248 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 3.43817 |
| MAP7 | microtubule-associated protein 7 | 3.42675 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.33286 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 3.26466 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.16449 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 3.06612 |
| CBR3 | carbonyl reductase 3 | 2.92317 |
| GPATCH8 | G patch domain containing 8 | 2.90215 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.81941 |
| KIF14 | kinesin family member 14 | 2.75153 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.73483 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.70123 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 2.63015 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.57845 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 2.5731 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.56467 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.41134 |
| PMM2 | phosphomannomutase 2 | 2.33132 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 2.28588 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.23579 |
| H2BC21 | H2B clustered histone 21 | 2.219 |
| SH3D19 | SH3 domain containing 19 | 2.1675 |
| FKBP4 | FK506 binding protein 4, 59kDa | 2.14732 |
| TRIM2 | tripartite motif containing 2 | 2.12431 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.08134 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.0449 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35F2 | solute carrier family 35, member F2 | -8.11615 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -6.08793 |
| HSPB1 | heat shock 27kDa protein 1 | -5.41538 |
| TRIB3 | tribbles pseudokinase 3 | -5.35299 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.01458 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.70311 |
| LOC124907782 | dual specificity protein phosphatase 22 | -4.65985 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.28678 |
| ADI1 | acireductone dioxygenase 1 | -4.267 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.20723 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.91577 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.8423 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.24637 |
| CCNB2 | cyclin B2 | -3.2358 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.18018 |
| CDC42 | cell division cycle 42 | -3.05474 |
| COG7 | component of oligomeric golgi complex 7 | -2.76773 |
| PCNA | proliferating cell nuclear antigen | -2.6593 |
| ICAM3 | intercellular adhesion molecule 3 | -2.45748 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.43683 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -2.413 |
| WBP1L | WW domain binding protein 1-like | -2.40949 |
| BATF | basic leucine zipper transcription factor, ATF-like | -2.38352 |
| HMOX1 | heme oxygenase 1 | -2.35187 |
| MAGEC1 | melanoma antigen family C1 | -2.34998 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | -2.2464 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -2.23717 |
| TCTN1 | tectonic family member 1 | -2.20364 |
| RBM47 | RNA binding motif protein 47 | -2.19572 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -2.05211 |
| PRPF4 | pre-mRNA processing factor 4 | -2.04368 |
| MAGEC2 | melanoma antigen family C2 | -2.04324 |
| IRF2 | interferon regulatory factor 2 | -2.0281 |
| CTSB | cathepsin B | -2.01306 |
| CTSS | cathepsin S | -2.00552 |
