CRCGN012_HEPG2_24H:A07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dl-menthol 41.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN012_HEPG2_24H:A07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 7.52197
CSK c-src tyrosine kinase 5.07882
CHMP6 charged multivesicular body protein 6 4.95989
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.88584
PPARG peroxisome proliferator-activated receptor gamma 4.44914
CCL2 chemokine (C-C motif) ligand 2 4.01394
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.92647
RRAGA Ras-related GTP binding A 3.66908
ZBTB35 zinc finger and BTB domain containing 35 3.62248
PMM2 phosphomannomutase 2 3.252
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.95239
TIAM1 T-cell lymphoma invasion and metastasis 1 2.85136
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.58813
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.29541
DONSON downstream neighbor of SON 2.21698
TBP TATA box binding protein 2.17687
SATB1 SATB homeobox 1 2.16243
ANO1 anoctamin 1, calcium activated chloride channel 2.10808
BAG3 BCL2-associated athanogene 3 2.03555
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.02488

decreased expression

Symbol Name Standardized Value
HSPB1 heat shock 27kDa protein 1 -5.49173
DHRS7 dehydrogenase/reductase (SDR family) member 7 -5.41703
CDC25B cell division cycle 25B -4.92062
ZFP36 ZFP36 ring finger protein -4.16259
CCNB1 cyclin B1 -3.78894
OXA1L oxidase (cytochrome c) assembly 1-like -3.51313
TWF2 twinfilin actin binding protein 2 -2.9998
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.82965
CDC42 cell division cycle 42 -2.78408
MAP7 microtubule-associated protein 7 -2.69811
EGF epidermal growth factor -2.49122
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.3102
PDZD2 PDZ domain containing 2 -2.30399
MRPL4 mitochondrial ribosomal protein L4 -2.07954
AKAP8 A kinase (PRKA) anchor protein 8 -2.06812
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.00558