| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dl-menthol 20.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN012_HEPG2_24H:A08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.90539 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 3.80168 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.75634 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.50883 |
| CSK | c-src tyrosine kinase | 3.47299 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.28507 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.26653 |
| E2F2 | E2F transcription factor 2 | 3.14973 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.11505 |
| LAGE3 | L antigen family, member 3 | 3.00212 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.97156 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.92204 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.84946 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.71868 |
| HSPA1A | heat shock 70kDa protein 1A | 2.61717 |
| CHN1 | chimerin 1 | 2.54509 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.38892 |
| FZD7 | frizzled class receptor 7 | 2.36386 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.3496 |
| PLSCR3 | phospholipid scramblase 3 | 2.31601 |
| WDR6 | WD repeat domain 6 | 2.31559 |
| RECQL4 | RecQ protein-like 4 | 2.30401 |
| KIF14 | kinesin family member 14 | 2.24188 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.09801 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 2.08932 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.05069 |
| RAD51C | RAD51 paralog C | 2.01283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM3A | lysine (K)-specific demethylase 3A | -6.31356 |
| GNAS | GNAS complex locus | -5.17466 |
| MAP7 | microtubule-associated protein 7 | -4.34885 |
| PCNA | proliferating cell nuclear antigen | -4.04773 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.99763 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.52142 |
| DSG2 | desmoglein 2 | -3.36571 |
| LAP3 | leucine aminopeptidase 3 | -3.3459 |
| TRIB3 | tribbles pseudokinase 3 | -3.29721 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.27289 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.2018 |
| THAP11 | THAP domain containing 11 | -3.18699 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.04631 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.02069 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.98594 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.98476 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.95624 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.95615 |
| LDHD | lactate dehydrogenase D | -2.89373 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.87719 |
| DNM1L | dynamin 1-like | -2.86299 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.78722 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.4902 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.39231 |
| SCAND1 | SCAN domain containing 1 | -2.34145 |
| BEX4 | brain expressed, X-linked 4 | -2.19675 |
| CCNB2 | cyclin B2 | -2.12573 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.00298 |
