CRCGN012_HEPG2_24H:A09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dl-menthol 10.25 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

43 genes differentially expressed following the CRCGN012_HEPG2_24H:A09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CIAO3 cytosolic iron-sulfur assembly component 3 6.34777
CSK c-src tyrosine kinase 6.33112
TIAM1 T-cell lymphoma invasion and metastasis 1 6.20657
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.81531
MAMLD1 mastermind-like domain containing 1 4.13837
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.91114
MYLK myosin light chain kinase 3.89703
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.66406
UBQLN2 ubiquilin 2 3.66049
HOXA10 homeobox A10 3.48538
BZW2 basic leucine zipper and W2 domains 2 3.44153
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.3451
STK10 serine/threonine kinase 10 3.02827
PPARG peroxisome proliferator-activated receptor gamma 2.92214
ANO1 anoctamin 1, calcium activated chloride channel 2.83916
SQOR sulfide quinone oxidoreductase 2.63145
CCNF cyclin F 2.62029
CHMP6 charged multivesicular body protein 6 2.61078
CYCS cytochrome c, somatic 2.46671
ADRB2 adrenoceptor beta 2, surface 2.39634
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.3691
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.32996
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.24633
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 2.09485
KIF14 kinesin family member 14 2.07547
NOSIP nitric oxide synthase interacting protein 2.01654

decreased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.18106
LDHD lactate dehydrogenase D -6.15045
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.22957
VAT1 vesicle amine transport 1 -4.0507
CCNB2 cyclin B2 -3.60621
PRPF4 pre-mRNA processing factor 4 -3.58253
NUP93 nucleoporin 93kDa -3.52134
MAP7 microtubule-associated protein 7 -3.32321
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.24935
FHL2 four and a half LIM domains 2 -3.12752
HAT1 histone acetyltransferase 1 -3.09921
DNM1L dynamin 1-like -2.94948
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.69798
MACF1 microtubule-actin crosslinking factor 1 -2.17961
YME1L1 YME1-like 1 ATPase -2.09753
CCDC86 coiled-coil domain containing 86 -2.08383
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.02059