CRCGN012_HEPG2_24H:A10 Gene Set
Genes
60 genes differentially expressed following the CRCGN012_HEPG2_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
6.67072
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
6.25407
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.78167
|
|
PRR15L
|
proline rich 15-like
|
4.90692
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.90107
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.64794
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.58235
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.55572
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.47009
|
|
MOK
|
MOK protein kinase
|
3.42496
|
|
NOTCH1
|
notch 1
|
3.33564
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.2218
|
|
RPL39L
|
ribosomal protein L39-like
|
3.18632
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.12975
|
|
MCOLN1
|
mucolipin 1
|
3.02898
|
|
HDGFL3
|
HDGF like 3
|
2.78624
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.78267
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.72517
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.72228
|
|
MAP7
|
microtubule-associated protein 7
|
2.70906
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.6791
|
|
CRTAP
|
cartilage associated protein
|
2.26861
|
|
LCN2
|
lipocalin 2
|
2.26765
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.26735
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.15883
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
2.14326
|
|
CCNF
|
cyclin F
|
2.14205
|
|
PRELID3B
|
PRELI domain containing 3B
|
2.12548
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.01281
|
|
MED4
|
mediator complex subunit 4
|
2.00531
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.53035
|
|
ADI1
|
acireductone dioxygenase 1
|
-7.23993
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.27433
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.66305
|
|
CCNB2
|
cyclin B2
|
-4.27019
|
|
GOLT1B
|
golgi transport 1B
|
-3.97901
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.80705
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.6964
|
|
PEG10
|
paternally expressed 10
|
-3.69073
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.67928
|
|
ZNF586
|
zinc finger protein 586
|
-3.60769
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.46763
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.38305
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.29994
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
-2.8161
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.73873
|
|
NISCH
|
nischarin
|
-2.61691
|
|
LDHD
|
lactate dehydrogenase D
|
-2.5489
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.54665
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.54246
|
|
NCK1
|
NCK adaptor protein 1
|
-2.53314
|
|
CD320
|
CD320 molecule
|
-2.38541
|
|
ETNK1
|
ethanolamine kinase 1
|
-2.37504
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.36786
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.36323
|
|
CPM
|
carboxypeptidase M
|
-2.19517
|
|
TASL
|
TLR adaptor interacting with endolysosomal SLC15A4
|
-2.17578
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.07013
|
|
NECTIN3
|
nectin cell adhesion molecule 3
|
-2.04444
|
|
GSDMB
|
gasdermin B
|
-2.03179
|
