CRCGN012_HEPG2_24H:A12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dl-menthol 1.28 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

61 genes differentially expressed following the CRCGN012_HEPG2_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 6.46404
CCDC92 coiled-coil domain containing 92 4.24276
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.91448
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.76746
LCN2 lipocalin 2 3.74555
CSK c-src tyrosine kinase 3.73661
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.65905
STIMATE STIM activating enhancer 3.49405
UBQLN2 ubiquilin 2 3.40778
PEX11A peroxisomal biogenesis factor 11 alpha 3.21607
CCDC85B coiled-coil domain containing 85B 3.1728
ADRB2 adrenoceptor beta 2, surface 3.09264
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 3.05464
BACE2 beta-site APP-cleaving enzyme 2 3.0431
JADE2 jade family PHD finger 2 2.83041
C2CD2 C2 calcium-dependent domain containing 2 2.76853
OXCT1 3-oxoacid CoA transferase 1 2.48607
IGFBP3 insulin-like growth factor binding protein 3 2.4363
CARMIL1 capping protein regulator and myosin 1 linker 1 2.42819
SH3D19 SH3 domain containing 19 2.42458
KLHL9 kelch-like family member 9 2.36199
MTERF3 mitochondrial transcription termination factor 3 2.32021
TPD52L2 tumor protein D52-like 2 2.30246
DHDDS dehydrodolichyl diphosphate synthase 2.21796
PRKX protein kinase, X-linked 2.21575
MOK MOK protein kinase 2.15341
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.15089
SIRT3 sirtuin 3 2.14163
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.09933
GPATCH8 G patch domain containing 8 2.07061
ADGRE5 adhesion G protein-coupled receptor E5 2.06241
RAB31 RAB31, member RAS oncogene family 2.06053
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 2.05213
CYB561 cytochrome b561 2.04984
TALDO1 transaldolase 1 2.04881
TBC1D10C TBC1 domain family, member 10C 2.04187
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.04177
RIC8A RIC8 guanine nucleotide exchange factor A 2.02105

decreased expression

Symbol Name Standardized Value
DNM1L dynamin 1-like -3.50311
COG2 component of oligomeric golgi complex 2 -3.41688
TM9SF3 transmembrane 9 superfamily member 3 -3.37973
ISOC1 isochorismatase domain containing 1 -3.24948
MAPK13 mitogen-activated protein kinase 13 -3.14365
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.98598
CRELD2 cysteine-rich with EGF-like domains 2 -2.84986
TUBB6 tubulin, beta 6 class V -2.84849
UGDH UDP-glucose 6-dehydrogenase -2.75058
ZNF586 zinc finger protein 586 -2.4747
PPP1R13B protein phosphatase 1, regulatory subunit 13B -2.38834
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.38428
WDR7 WD repeat domain 7 -2.28136
TCTN1 tectonic family member 1 -2.2609
NVL nuclear VCP-like -2.15818
TGFB3 transforming growth factor, beta 3 -2.1163
CD320 CD320 molecule -2.11285
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.10025
RAI14 retinoic acid induced 14 -2.09395
TOMM34 translocase of outer mitochondrial membrane 34 -2.04513
ZBTB22 zinc finger and BTB domain containing 22 -2.03536
ZNHIT2 zinc finger, HIT-type containing 2 -2.01446
CCNB2 cyclin B2 -2.00559