CRCGN012_HEPG2_24H:A14 Gene Set
Genes
45 genes differentially expressed following the CRCGN012_HEPG2_24H:A14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.72901
|
|
PRR15L
|
proline rich 15-like
|
5.03687
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.00995
|
|
CHN1
|
chimerin 1
|
4.53357
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.42196
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.22414
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.10069
|
|
ABHD4
|
abhydrolase domain containing 4
|
4.00083
|
|
KLHL21
|
kelch-like family member 21
|
3.71687
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.47575
|
|
SCRN1
|
secernin 1
|
3.46747
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.36775
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.30513
|
|
EVL
|
Enah/Vasp-like
|
3.29757
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.16575
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
3.02931
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.89711
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.84738
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.26311
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.2377
|
|
NUCB2
|
nucleobindin 2
|
2.11696
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.42875
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.2736
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-6.95447
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.43447
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.05635
|
|
PLK1
|
polo-like kinase 1
|
-3.77884
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.68739
|
|
MAP7
|
microtubule-associated protein 7
|
-3.6501
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.43525
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.22306
|
|
ZNF586
|
zinc finger protein 586
|
-3.20452
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.9579
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.81421
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.75588
|
|
EGF
|
epidermal growth factor
|
-2.62361
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.58073
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.47255
|
|
CPNE3
|
copine III
|
-2.28816
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.23887
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.20708
|
|
RAI14
|
retinoic acid induced 14
|
-2.08443
|
|
SCN2A
|
sodium channel, voltage gated, type II alpha subunit
|
-2.08435
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.05878
|
|
KRT31
|
keratin 31, type I
|
-2.04175
|
