CRCGN012_HEPG2_24H:A15 Gene Set
Genes
40 genes differentially expressed following the CRCGN012_HEPG2_24H:A15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.38065
|
|
CSK
|
c-src tyrosine kinase
|
4.25178
|
|
LCN2
|
lipocalin 2
|
4.12306
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.70982
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.21146
|
|
PRKCH
|
protein kinase C, eta
|
3.14625
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
3.10723
|
|
MYLK
|
myosin light chain kinase
|
3.07042
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.93312
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.90782
|
|
CHEK2
|
checkpoint kinase 2
|
2.77534
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.73684
|
|
EPHA3
|
EPH receptor A3
|
2.61291
|
|
VGLL4
|
vestigial-like family member 4
|
2.59742
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.46278
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.39503
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.38998
|
|
RPL39L
|
ribosomal protein L39-like
|
2.35703
|
|
STK10
|
serine/threonine kinase 10
|
2.31777
|
|
HAT1
|
histone acetyltransferase 1
|
2.22803
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.14112
|
|
TBP
|
TATA box binding protein
|
2.13405
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.01135
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-6.35183
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.94115
|
|
LDHD
|
lactate dehydrogenase D
|
-5.37892
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.88397
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.81846
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.80672
|
|
CCNB1
|
cyclin B1
|
-3.32016
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.281
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.26065
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.17279
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.76713
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.64766
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.41835
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.27074
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.23185
|
|
RNF167
|
ring finger protein 167
|
-2.22717
|
|
ENOPH1
|
enolase-phosphatase 1
|
-2.07825
|
