CRCGN012_HEPG2_24H:A16 Gene Set
Genes
42 genes differentially expressed following the CRCGN012_HEPG2_24H:A16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.25109
|
|
CHN1
|
chimerin 1
|
4.75994
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
4.40645
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.34109
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.98837
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.92768
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.78635
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.59836
|
|
LCN2
|
lipocalin 2
|
3.57508
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.52229
|
|
PRKCH
|
protein kinase C, eta
|
3.50625
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.22938
|
|
STIMATE
|
STIM activating enhancer
|
3.06752
|
|
INSIG1
|
insulin induced gene 1
|
2.71527
|
|
GATA3
|
GATA binding protein 3
|
2.6171
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.60532
|
|
KLHL21
|
kelch-like family member 21
|
2.55465
|
|
EVL
|
Enah/Vasp-like
|
2.38826
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.32069
|
|
NUP85
|
nucleoporin 85kDa
|
2.30883
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.2722
|
|
SYNGR3
|
synaptogyrin 3
|
2.18507
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.08851
|
|
GPATCH8
|
G patch domain containing 8
|
2.06626
|
|
SATB1
|
SATB homeobox 1
|
2.0528
|
|
SLC25A46
|
solute carrier family 25, member 46
|
2.02055
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-6.36698
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-3.7621
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.6462
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.56929
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.53141
|
|
CCNB2
|
cyclin B2
|
-3.49778
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.45939
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.08295
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.99955
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.73182
|
|
TSPAN4
|
tetraspanin 4
|
-2.46403
|
|
BDH1
|
3-hydroxybutyrate dehydrogenase, type 1
|
-2.31764
|
|
BCL7B
|
B-cell CLL/lymphoma 7B
|
-2.21204
|
|
CEP83
|
centrosomal protein 83kDa
|
-2.18022
|
|
SPEF1
|
sperm flagellar 1
|
-2.00811
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.00789
|