CRCGN012_HEPG2_24H:A17 Gene Set
Genes
38 genes differentially expressed following the CRCGN012_HEPG2_24H:A17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.63025
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.72817
|
|
CSK
|
c-src tyrosine kinase
|
4.69937
|
|
PRR15L
|
proline rich 15-like
|
4.5556
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.4722
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.1073
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.0753
|
|
IDE
|
insulin-degrading enzyme
|
3.38332
|
|
EGF
|
epidermal growth factor
|
3.26745
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.1245
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.05303
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.75822
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
2.52211
|
|
MOK
|
MOK protein kinase
|
2.49217
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.48134
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.39343
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.38298
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.31604
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.2264
|
|
CHN1
|
chimerin 1
|
2.18181
|
|
RPL39L
|
ribosomal protein L39-like
|
2.17218
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.10764
|
|
ZNF589
|
zinc finger protein 589
|
2.05891
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-5.92176
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.09974
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.92338
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.73472
|
|
CCNB1
|
cyclin B1
|
-2.72308
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.6225
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.42209
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.3356
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.29459
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.26397
|
|
CAMK2N1
|
calcium/calmodulin-dependent protein kinase II inhibitor 1
|
-2.18744
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.17818
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.03706
|
|
MNT
|
MAX network transcriptional repressor
|
-2.02371
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.02146
|
