| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p-anisidine.hcl 39.4 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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63 genes differentially expressed following the CRCGN012_HEPG2_24H:A19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EVL | Enah/Vasp-like | 4.71998 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 3.88687 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.88189 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.62538 |
| CCNF | cyclin F | 3.61712 |
| NUCB2 | nucleobindin 2 | 3.48018 |
| UBQLN2 | ubiquilin 2 | 3.36066 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.35666 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.14808 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 3.04135 |
| STXBP2 | syntaxin binding protein 2 | 2.86925 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.75374 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 2.58894 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.5208 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.47403 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.41464 |
| FZD7 | frizzled class receptor 7 | 2.40772 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.36987 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 2.30128 |
| CHMP6 | charged multivesicular body protein 6 | 2.26679 |
| NCBP3 | nuclear cap binding subunit 3 | 2.25463 |
| RAB31 | RAB31, member RAS oncogene family | 2.24134 |
| STIMATE | STIM activating enhancer | 2.20307 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.16377 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.14483 |
| CYCS | cytochrome c, somatic | 2.10683 |
| ABHD4 | abhydrolase domain containing 4 | 2.09741 |
| CBR3 | carbonyl reductase 3 | 2.08103 |
| MAP7 | microtubule-associated protein 7 | 2.05989 |
| STK10 | serine/threonine kinase 10 | 2.00656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.60707 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.45541 |
| TRIB3 | tribbles pseudokinase 3 | -5.00518 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.80634 |
| WASHC4 | WASH complex subunit 4 | -4.31337 |
| CCNB2 | cyclin B2 | -4.0806 |
| ZNF586 | zinc finger protein 586 | -3.95934 |
| CAB39 | calcium binding protein 39 | -3.61265 |
| VAT1 | vesicle amine transport 1 | -3.47931 |
| CDC25B | cell division cycle 25B | -3.34076 |
| PEG10 | paternally expressed 10 | -3.01353 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.00357 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.959 |
| DSG2 | desmoglein 2 | -2.78188 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.76426 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.6389 |
| NGRN | neugrin, neurite outgrowth associated | -2.63657 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.50543 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.42851 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.3805 |
| TRIM39-RPP21 | TRIM39-RPP21 readthrough | -2.31956 |
| GNAS | GNAS complex locus | -2.24906 |
| EXT1 | exostosin glycosyltransferase 1 | -2.1987 |
| EDN1 | endothelin 1 | -2.14618 |
| FRMD1 | FERM domain containing 1 | -2.12783 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.12145 |
| FZD8 | frizzled class receptor 8 | -2.08821 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.06591 |
| CALB2 | calbindin 2 | -2.06448 |
| COG7 | component of oligomeric golgi complex 7 | -2.05747 |
| RAI14 | retinoic acid induced 14 | -2.05265 |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 | -2.03798 |
| SV2C | synaptic vesicle glycoprotein 2C | -2.01657 |