CRCGN012_HEPG2_24H:A19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-anisidine.hcl 39.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

63 genes differentially expressed following the CRCGN012_HEPG2_24H:A19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EVL Enah/Vasp-like 4.71998
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.88687
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.88189
C2CD2 C2 calcium-dependent domain containing 2 3.62538
CCNF cyclin F 3.61712
NUCB2 nucleobindin 2 3.48018
UBQLN2 ubiquilin 2 3.36066
RPP38 ribonuclease P/MRP 38kDa subunit 3.35666
RXYLT1 ribitol xylosyltransferase 1 3.14808
ZBTB35 zinc finger and BTB domain containing 35 3.04135
STXBP2 syntaxin binding protein 2 2.86925
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.75374
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.58894
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.5208
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.47403
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.41464
FZD7 frizzled class receptor 7 2.40772
LPAR2 lysophosphatidic acid receptor 2 2.36987
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.30128
CHMP6 charged multivesicular body protein 6 2.26679
NCBP3 nuclear cap binding subunit 3 2.25463
RAB31 RAB31, member RAS oncogene family 2.24134
STIMATE STIM activating enhancer 2.20307
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.16377
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.14483
CYCS cytochrome c, somatic 2.10683
ABHD4 abhydrolase domain containing 4 2.09741
CBR3 carbonyl reductase 3 2.08103
MAP7 microtubule-associated protein 7 2.05989
STK10 serine/threonine kinase 10 2.00656

decreased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -5.60707
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.45541
TRIB3 tribbles pseudokinase 3 -5.00518
MAPK13 mitogen-activated protein kinase 13 -4.80634
WASHC4 WASH complex subunit 4 -4.31337
CCNB2 cyclin B2 -4.0806
ZNF586 zinc finger protein 586 -3.95934
CAB39 calcium binding protein 39 -3.61265
VAT1 vesicle amine transport 1 -3.47931
CDC25B cell division cycle 25B -3.34076
PEG10 paternally expressed 10 -3.01353
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.00357
OXA1L oxidase (cytochrome c) assembly 1-like -2.959
DSG2 desmoglein 2 -2.78188
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.76426
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.6389
NGRN neugrin, neurite outgrowth associated -2.63657
TOMM34 translocase of outer mitochondrial membrane 34 -2.50543
CRELD2 cysteine-rich with EGF-like domains 2 -2.42851
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.3805
TRIM39-RPP21 TRIM39-RPP21 readthrough -2.31956
GNAS GNAS complex locus -2.24906
EXT1 exostosin glycosyltransferase 1 -2.1987
EDN1 endothelin 1 -2.14618
FRMD1 FERM domain containing 1 -2.12783
EIF5 eukaryotic translation initiation factor 5 -2.12145
FZD8 frizzled class receptor 8 -2.08821
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.06591
CALB2 calbindin 2 -2.06448
COG7 component of oligomeric golgi complex 7 -2.05747
RAI14 retinoic acid induced 14 -2.05265
ELAVL4 ELAV like neuron-specific RNA binding protein 4 -2.03798
SV2C synaptic vesicle glycoprotein 2C -2.01657