CRCGN012_HEPG2_24H:A21 Gene Set
Genes
37 genes differentially expressed following the CRCGN012_HEPG2_24H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.64555
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.47709
|
|
CSK
|
c-src tyrosine kinase
|
5.12867
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.80416
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
4.35511
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.52928
|
|
SATB1
|
SATB homeobox 1
|
3.25029
|
|
STK10
|
serine/threonine kinase 10
|
3.11861
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.73364
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.71002
|
|
CYCS
|
cytochrome c, somatic
|
2.66648
|
|
CCNF
|
cyclin F
|
2.62476
|
|
SFTPB
|
surfactant protein B
|
2.20569
|
|
TBP
|
TATA box binding protein
|
2.16105
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.11585
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.08685
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.03164
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.02068
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-5.08732
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.83969
|
|
EGF
|
epidermal growth factor
|
-4.18719
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.0052
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-3.99055
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.33857
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.15405
|
|
SNX11
|
sorting nexin 11
|
-3.11663
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.08781
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.52844
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.44927
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.32368
|
|
CCNB1
|
cyclin B1
|
-2.31225
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.2
|
|
TMOD3
|
tropomodulin 3 (ubiquitous)
|
-2.15699
|
|
CDC20
|
cell division cycle 20
|
-2.14964
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.05631
|
|
NIPSNAP2
|
nipsnap homolog 2
|
-2.03793
|
