| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p-anisidine.hcl 4.92 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN012_HEPG2_24H:A22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 5.80616 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.39447 |
| CYCS | cytochrome c, somatic | 5.37114 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.24434 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.74739 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.64026 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.44653 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 4.10138 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.95326 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.91986 |
| LCN2 | lipocalin 2 | 3.89754 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.84012 |
| ABHD6 | abhydrolase domain containing 6 | 3.61127 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.4373 |
| GPATCH8 | G patch domain containing 8 | 2.99421 |
| PRKCH | protein kinase C, eta | 2.96582 |
| SCRN1 | secernin 1 | 2.58559 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 2.54226 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 2.40973 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | 2.35847 |
| CHEK2 | checkpoint kinase 2 | 2.33901 |
| NENF | neudesin neurotrophic factor | 2.32512 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.29715 |
| DGAT1 | diacylglycerol O-acyltransferase 1 | 2.24614 |
| NEFM | neurofilament, medium polypeptide | 2.22553 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 | 2.12679 |
| JADE2 | jade family PHD finger 2 | 2.12066 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 2.12028 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain | 2.118 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 2.09805 |
| TMEM260 | transmembrane protein 260 | 2.07272 |
| AFTPH | aftiphilin | 2.01972 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -8.64138 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -8.36813 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.37927 |
| ADI1 | acireductone dioxygenase 1 | -4.75472 |
| FASTKD5 | FAST kinase domains 5 | -4.62021 |
| CAB39 | calcium binding protein 39 | -4.4676 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.35104 |
| THAP11 | THAP domain containing 11 | -4.27542 |
| TRIB3 | tribbles pseudokinase 3 | -3.90946 |
| SMNDC1 | survival motor neuron domain containing 1 | -3.8987 |
| PGAM4 | phosphoglycerate mutase family member 4 | -3.80721 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.36623 |
| SLC35F2 | solute carrier family 35, member F2 | -3.02317 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -2.853 |
| ZBP1 | Z-DNA binding protein 1 | -2.65919 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.45074 |
| ADCY7 | adenylate cyclase 7 | -2.43789 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.39788 |
| IL5 | interleukin 5 | -2.3386 |
| RAI14 | retinoic acid induced 14 | -2.30223 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -2.24602 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa | -2.1982 |
| CLEC7A | C-type lectin domain family 7, member A | -2.14834 |
| USP6NL | USP6 N-terminal like | -2.1419 |
| UBASH3A | ubiquitin associated and SH3 domain containing A | -2.14003 |
| ATF5 | activating transcription factor 5 | -2.119 |
| UBXN8 | UBX domain protein 8 | -2.09904 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 | -2.08064 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -2.08049 |
| ESYT1 | extended synaptotagmin-like protein 1 | -2.06848 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | -2.05159 |
| SAE1 | SUMO1 activating enzyme subunit 1 | -2.03868 |
| TRADD | TNFRSF1A-associated via death domain | -2.02842 |
| TRIM68 | tripartite motif containing 68 | -2.02468 |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 | -2.01865 |
| ABCB11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | -2.01704 |
| TMEM186 | transmembrane protein 186 | -2.01652 |
| WNT7A | wingless-type MMTV integration site family, member 7A | -2.00878 |
| OBP2B | odorant binding protein 2B | -2.00354 |
