CRCGN012_HEPG2_24H:A23 Gene Set
Genes
47 genes differentially expressed following the CRCGN012_HEPG2_24H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
6.93421
|
|
RPL39L
|
ribosomal protein L39-like
|
4.44802
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.36169
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.21867
|
|
STK10
|
serine/threonine kinase 10
|
4.13407
|
|
CBR3
|
carbonyl reductase 3
|
4.03052
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.8457
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.76131
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
3.68666
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.66166
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.61722
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.46389
|
|
HDGFL3
|
HDGF like 3
|
3.39217
|
|
E2F2
|
E2F transcription factor 2
|
3.32217
|
|
CCNF
|
cyclin F
|
3.22644
|
|
LCN2
|
lipocalin 2
|
2.81038
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.42059
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.26775
|
|
MYLK
|
myosin light chain kinase
|
2.18781
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.16245
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.14561
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.14247
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.12779
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.1235
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.1052
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
2.04066
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-5.9641
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-5.72915
|
|
CCNB2
|
cyclin B2
|
-4.81653
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.68525
|
|
MAP7
|
microtubule-associated protein 7
|
-3.97131
|
|
LDHD
|
lactate dehydrogenase D
|
-3.90869
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.72774
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.68042
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.57308
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.35911
|
|
DNM1L
|
dynamin 1-like
|
-3.31869
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.2881
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.28584
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.6771
|
|
GNAS
|
GNAS complex locus
|
-2.64138
|
|
P2RX5
|
purinergic receptor P2X, ligand gated ion channel, 5
|
-2.5257
|
|
SLC10A2
|
solute carrier family 10 (sodium/bile acid cotransporter), member 2
|
-2.39427
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.20629
|
|
RAI14
|
retinoic acid induced 14
|
-2.19092
|
|
SCYL2
|
SCY1-like 2 (S. cerevisiae)
|
-2.01742
|
|
ITGA2B
|
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
|
-2.00908
|
