CRCGN012_HEPG2_24H:B03 Gene Set
Genes
44 genes differentially expressed following the CRCGN012_HEPG2_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
8.67124
|
|
LCN2
|
lipocalin 2
|
4.3959
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.32497
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.29109
|
|
UBQLN2
|
ubiquilin 2
|
4.19754
|
|
TBXA2R
|
thromboxane A2 receptor
|
4.12749
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.91116
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.7305
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.29686
|
|
VGLL4
|
vestigial-like family member 4
|
3.22733
|
|
PRR15L
|
proline rich 15-like
|
3.01368
|
|
STXBP1
|
syntaxin binding protein 1
|
3.00258
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.91813
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.91545
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.76912
|
|
GPATCH8
|
G patch domain containing 8
|
2.55952
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.49687
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.36298
|
|
MEST
|
mesoderm specific transcript
|
2.26124
|
|
CHEK2
|
checkpoint kinase 2
|
2.20194
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.18768
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.08191
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.07022
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.01861
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PLK1
|
polo-like kinase 1
|
-4.5182
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.43357
|
|
GNAS
|
GNAS complex locus
|
-4.33137
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.15862
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.13913
|
|
KTN1
|
kinectin 1 (kinesin receptor)
|
-3.38025
|
|
CCNB2
|
cyclin B2
|
-3.36027
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.19287
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-3.08651
|
|
EGF
|
epidermal growth factor
|
-3.08328
|
|
FBXO7
|
F-box protein 7
|
-2.73457
|
|
EHD4
|
EH-domain containing 4
|
-2.37938
|
|
PLPPR1
|
phospholipid phosphatase related 1
|
-2.37015
|
|
CORO7-PAM16
|
CORO7-PAM16 readthrough
|
-2.32151
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.31864
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.20913
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.19773
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.14265
|
|
BBS7
|
Bardet-Biedl syndrome 7
|
-2.02172
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.01176
|
