CRCGN012_HEPG2_24H:B04 Gene Set
Genes
42 genes differentially expressed following the CRCGN012_HEPG2_24H:B04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
6.30166
|
|
CHN1
|
chimerin 1
|
4.30104
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.24039
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.94514
|
|
HOXA10
|
homeobox A10
|
3.657
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
3.55515
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.50279
|
|
E2F2
|
E2F transcription factor 2
|
3.40532
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.30368
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.18217
|
|
CBR3
|
carbonyl reductase 3
|
3.09662
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.89914
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.86031
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.84036
|
|
STK10
|
serine/threonine kinase 10
|
2.55871
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.41943
|
|
FZD7
|
frizzled class receptor 7
|
2.34949
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.2857
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.2257
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
2.21124
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.14068
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.13018
|
|
PFKL
|
phosphofructokinase, liver
|
2.01952
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.92246
|
|
CDC20
|
cell division cycle 20
|
-3.76615
|
|
GDF15
|
growth differentiation factor 15
|
-3.58429
|
|
VAT1
|
vesicle amine transport 1
|
-3.45079
|
|
CAB39
|
calcium binding protein 39
|
-3.31562
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.2867
|
|
SCAND1
|
SCAN domain containing 1
|
-3.20581
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.13112
|
|
ZNF586
|
zinc finger protein 586
|
-2.79848
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.62459
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.46414
|
|
RNF167
|
ring finger protein 167
|
-2.28358
|
|
CD58
|
CD58 molecule
|
-2.27311
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.22784
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.18699
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.13413
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.09609
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.07855
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.0272
|
