CRCGN012_HEPG2_24H:B05 Gene Set
Genes
58 genes differentially expressed following the CRCGN012_HEPG2_24H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.54355
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.93815
|
|
UBQLN2
|
ubiquilin 2
|
4.8225
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.80905
|
|
STIMATE
|
STIM activating enhancer
|
4.80575
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.63685
|
|
CCNA1
|
cyclin A1
|
4.56685
|
|
CSK
|
c-src tyrosine kinase
|
4.5113
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.47015
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.26235
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.8946
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.86685
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
3.6662
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.41197
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.39725
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.28765
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.22288
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.99022
|
|
CYCS
|
cytochrome c, somatic
|
2.8364
|
|
SATB1
|
SATB homeobox 1
|
2.8234
|
|
SH3D19
|
SH3 domain containing 19
|
2.81635
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.7501
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.7265
|
|
IDE
|
insulin-degrading enzyme
|
2.65668
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.6409
|
|
MMP1
|
matrix metallopeptidase 1
|
2.54175
|
|
PMM2
|
phosphomannomutase 2
|
2.4895
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.3277
|
|
ZNF589
|
zinc finger protein 589
|
2.28193
|
|
VGLL4
|
vestigial-like family member 4
|
2.2131
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.15015
|
|
BLMH
|
bleomycin hydrolase
|
2.12545
|
|
TAOK3
|
TAO kinase 3
|
2.08535
|
|
CCNF
|
cyclin F
|
2.03422
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCDC86
|
coiled-coil domain containing 86
|
-5.9635
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-5.5421
|
|
GDF15
|
growth differentiation factor 15
|
-5.44415
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.3606
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.3106
|
|
VAT1
|
vesicle amine transport 1
|
-5.0908
|
|
ZNF586
|
zinc finger protein 586
|
-5.0
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.93385
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.86355
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.74165
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.5992
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.50935
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.26075
|
|
PEG10
|
paternally expressed 10
|
-3.7092
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.2385
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.94635
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.8766
|
|
ZW10
|
zw10 kinetochore protein
|
-2.4614
|
|
EGF
|
epidermal growth factor
|
-2.29845
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.24025
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.22915
|
|
NR0B2
|
nuclear receptor subfamily 0, group B, member 2
|
-2.2014
|
|
KRT15
|
keratin 15, type I
|
-2.06605
|
|
DNAJA2
|
DnaJ (Hsp40) homolog, subfamily A, member 2
|
-2.01215
|
